The efficacy of enucleation and brachitherapy is assessed in 1150 patients. The incidence of metastases is the highest (up to 2/3) occurs within the first 3 years. Neither enucleation, nor brachitherapy affect this value. However, in general after enucleation the incidence of metastases to the liver (31.7%) is higher than after brachitherapy (5.8%), this indicating that brachitherapy is more effective in minor and medium-sized melanomas of the choroid.

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