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Zinc Deficiency Exacerbates Lead-Induced Interleukin-2 Suppression by Regulating CREM Expression.
Int J Mol Sci
December 2024
Institute of Immunology, Faculty of Medicine, RWTH Aachen University Hospital, Pauwelsstraße 30, 52074 Aachen, Germany.
Lead, a prevalent heavy metal, impairs the immune system by affecting T cell function. Similarly, zinc deficiency adversely affects T cells, with zinc deficiency and lead exposure being linked to reduced interleukin-2 (IL-2) production. Zinc deficiency has been associated with increased expression of the transcription factor CREM 100 kDa, which downregulates IL-2.
View Article and Find Full Text PDFMyco-assisted phytoextraction of heavy metals with vetiver grass: a green technology for cleaning tannery effluent contaminated sites.
Environ Monit Assess
November 2024
Nammazhvar Organic Farming Research Centre, Tamil Nadu Agricultural University, Coimbatore, 641003, Tamil Nadu, India.
Article Synopsis
- Metal toxicity impacts plant physiology, and mycorrhizal fungi (AMF) offer a new eco-friendly method to improve soil contaminated by tannery effluents, which are high in harmful metals like chromium and cadmium.* -
- A study was conducted using vetiver grass and three strains of AMF on contaminated soil from Tamil Nadu, revealing that AMF inoculation, particularly with R. intraradices, boosted plant growth and biomass significantly compared to other treatments.* -
- Results indicated that R. intraradices improved the phytoextraction of metals, reduced their movement into plant shoots, and increased carbon storage in vetiver, enhancing overall carbon sequestration in contaminated soil.*
Protective Role of Vitamin B6 Against Teratogenic Effects Induced by Lead in Chick Embryo.
Birth Defects Res
December 2024
Department of Zoology, University of Sargodha, Sargodha, Punjab, Pakistan.
Article Synopsis
- Lead exposure has increased since the industrial revolution, posing serious health risks as it serves no purpose in the human body and is still used in various industries, like battery manufacturing.* -
- This study examined the harmful effects of lead on chick embryos, noting significant growth reductions and deformities, while also assessing the potential of vitamin B6 to counteract these effects.* -
- Results showed that vitamin B6 improved embryo weight and reduced lead's negative impacts, indicating it may help protect against lead toxicity during development.*
Factors affecting the concentration of metals and metalloids in the kidneys of a top predator, the Eurasian Buzzard (Buteo buteo) wintering in farmland in Poland.
Environ Sci Pollut Res Int
November 2024
Department of Biosystem Engineering, Faculty of Environmental Engineering and Mechanical Engineering, Poznań University of Life Sciences, Wojska Polskiego 50, 60-627, Poznań, Poland.
Article Synopsis
- During late autumn and winter, Common Buzzards in Eastern Poland face food shortages and exposure to toxic elements, as highlighted by analyzing kidney samples from 41 raptors.
- The study found that a small percentage of these birds had harmful levels of lead (4.9%) and cadmium (9.8%), indicating potential poisoning risks in their environment.
- Additionally, the research showed differences in elemental accumulation between male and female buzzards, with females accumulating more lead and vanadium, and it suggested that dietary elements like zinc and selenium may help mitigate the toxic effects of heavy metals like lead and mercury.
Lead's Last Mile.
Pediatrics
October 2024
National Center for Environmental Health, Agency for Toxic Substances and Disease Registry, Centers for Disease Control and Prevention, Atlanta, Georgia.
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