The authors studied morphological changes in renal tissue in terminal hydronephrosis and in exposure of freezing, regulation of arterial pressure and erythropoiesis in cryogenic effects on hydronephrotic kidney in experiment. Reparative changes in the parenchyma appear on day 30 after freezing, systemic arterial pressure and bone marrow erythropoietic activity returned to normal. Freezing is thought more physiological compared to nephrectomy in respect to prevention of nephrogenic hypertension and anemia.

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