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Occupational anaphylaxis: A Position Paper of the German Society of Allergology and Clinical Immunology (DGAKI).
Allergol Select
November 2024
Department of Dermatology and Allergy Biederstein, School of Medicine and Health, Technical University of Munich TUM).
Background: Anaphylaxis is a systemic allergic reaction that is potentially life-threatening. Occupational anaphylaxis is an anaphylaxis that occurs in an occupational context. In this position paper, we propose diagnostic criteria for occupational anaphylaxis and provide an overview of the current state of knowledge in terms of prevalence, triggers, prevention, and management.
View Article and Find Full Text PDFDetection of anti-leptospiral antibodies using recombinant ErpY-like lipoprotein based latex agglutination test for serodiagnosis of animal leptospirosis.
Lett Appl Microbiol
November 2024
Indian Council of Agricultural Research-National Institute of Veterinary Epidemiology and Disease Informatics (ICAR-NIVEDI), Yelahanka, Bengaluru 560064, India.
Article Synopsis
- Timely diagnosis of leptospirosis is crucial for preventing severe health outcomes in both humans and animals, and current diagnostic methods have limitations that necessitate new approaches.
- This study explores a novel diagnostic tool using a recombinant lipoprotein (rErpY-LIC11966) in a latex agglutination test (LAT), which was developed and tested for its effectiveness in diagnosing animal leptospirosis.
- The rErpY-LAT demonstrated high diagnostic performance, with 90.6% sensitivity, 89.1% specificity, and 90% overall accuracy, making it a promising field-applicable option for early serodiagnosis of the disease.
Contents of sensitising rubber accelerators in disposable rubber gloves: A Copenhagen market survey.
Contact Dermatitis
February 2025
Department of Occupational and Environmental Dermatology, Lund University, Skåne University Hospital, Malmö, Sweden.
Article Synopsis
- Rubber gloves often have rubber accelerators that can cause allergic reactions, but their specific content is not well understood.
- A study tested 51 gloves from various brands, finding that 90% of disposable gloves contained sensitizing rubber accelerators, particularly zinc dibutyldithiocarbamate (ZDBC) and zinc diethyldithiocarbamate (ZDEC).
- The research highlights the need for better labeling of rubber gloves, as even those claimed to be free of accelerators were found to have them, necessitating more transparency from manufacturers.
Sensitization to latex and food allergens in atopic dermatitis patients according to ALEX2 Allergy Xplorer test.
Mol Immunol
November 2024
Department of Clinical Immunology and Allergy, Faculty Hospital and Medical Faculty of Charles University, Hradec Králové 50002, Czech Republic. Electronic address:
Article Synopsis
- The study aimed to analyze the sensitization to latex and food allergens in atopic dermatitis patients using the ALEX2 Allergy Xplorer test, comparing the results with personal histories of allergies.
- The study included 100 patients, examining specific IgE responses to latex and collecting detailed allergy histories.
- The findings revealed 17% sensitization to latex, primarily linked to specific protein components, with some patients showing allergic reactions to latex or related fruit syndromes, underscoring the connections between molecular components and clinical reactions.
NIR-triggered upconversion and sensitized NIR-emission in Yb-based Eosin Y lake doped latex nanoparticles.
Phys Chem Chem Phys
September 2024
Instituto de Ciencia Molecular (ICMol), Universitat de València, Catedrático José Beltrán 2, Paterna, 46980 Valencia, Spain.
Here, Yb-based Eosin Y lakes (EOS-Yb) have been encapsulated in organic nanoparticles (NPs) by microemulsion radical polymerization of methacrylate-based copolymers. These photoactive EOS-Yb NPs emit in the visible and near infrared (NIR) upon excitation at 530 nm and can also display NIR-to-visible upconversion emission upon excitation at 980 nm.
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