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http://dx.doi.org/10.1016/s0163-4453(98)80033-9 | DOI Listing |
Life (Basel)
December 2024
2nd Department of Obstetrics and Gynecology, 'Iuliu Hatieganu' University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania.
Parvovirus B19 (B19V) infection is the cause of erythema infectiosum, or the "fifth disease", a widespread infection, potentially affecting 1-5% of pregnant women, in most cases without significant damage to the pregnancy or fetus. It follows a seasonal variation, with a higher prevalence in temperate climates, mainly in late winter and early spring. Women at increased risk include mothers of preschool and school-age children, and those working in nurseries, kindergartens, and schools.
View Article and Find Full Text PDFItal J Pediatr
December 2024
Department of Pediatrics, Santa Maria delle Croci Hospital, AUSL della Romagna, Viale Vincenzo Randi, 5, Ravenna, Ravenna, 48121, RA, Italy.
Parvovirus B19 (B19V) is a significant pathogen responsible for a wide range of clinical manifestations, particularly in children and pregnant women. While B19V is most commonly recognized as the cause of Fifth disease, a mild erythematous illness in children, its clinical impact extends far beyond this condition. B19V can lead to severe complications, including transient aplastic crisis in individuals with chronic hemolytic anemias, arthralgia, and more severe joint diseases.
View Article and Find Full Text PDFRev Fac Cien Med Univ Nac Cordoba
December 2024
Universidad Nacional de Córdoba.
Introduction: parvovirus B19 (B19V) infection during pregnancy can be transmitted to the fetus and cause serious complications such as fetal hydrops and stillbirth. The preexistence of specific IgG prevents vertical transmission. Seroprevalence in fertile age is variable (50-70%) and depends on the region/viral circulation, in addition to factors such as maternal age and frequent exposure to children.
View Article and Find Full Text PDFVet Res
November 2024
College of Veterinary Medicine, Northwest A&F University, Yangling, China.
Porcine parvovirus (PPV) infection induces germ cell death, leading to reproductive disorders in first-pregnant sows. Porcine placental trophoblast cells (PTCs) are the major target of PPV, and we have previously found that PPV infection leads to the death of PTCs by a non-apoptotic process, which may be related to PPV pathogenicity. The Z-nucleic acid-binding protein 1 (ZBP1) is often activated after virus invasion and mediates subsequent cell death.
View Article and Find Full Text PDFViruses
October 2024
Feto Maternal Centre, Al Markhiya Doha, Doha P.O. Box 34181, Qatar.
Viruses are the most common congenital infections in humans and an important cause of foetal malformations, neonatal morbidity, and mortality. The effects of these infections, which are transmitted in utero (transplacentally), during childbirth or in the puerperium depend on the timing of the infections. These vary from miscarriages (usually with infections in very early pregnancy), congenital malformations (when the infections occur during organogenesis) and morbidity (with infections occurring late in pregnancy, during childbirth or after delivery).
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