Previous family history studies have demonstrated that there are elevated rates of language and language-related impairments in families identified through probands with language impairments. This study examines family histories of children with specific language impairment (SLI) known to have particular grammatical limitations in a core feature of grammatical acquisition, a stage known as Extended Optional Infinitives (EOI). Family affectedness rates are reported for 31 families identified through preschool probands with this clearly defined language impairment and 67 control families, identified through nonaffected preschool children developmentally similar to the probands. It was found that significantly more speech and language difficulties, as well as language-related difficulties, such as reading, were reported for proband families than control families. The elevated rates were obtained for nuclear family members and extended family members as well. Fathers of probands were more often reported as having difficulties (29% for speech/language impairments) than were mothers of probands (7%), but there was no difference between brothers (26%) and sisters (29%). No differences were evident between proband families based on proband gender. The findings are relevant for theoretical models of sources of unexplained variations in grammatical competence in young children. In addition, the findings contribute new information about expected rates of affectedness, means of identification of affected family members, and comorbidity of symptomatology.
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http://dx.doi.org/10.1044/jslhr.4102.419 | DOI Listing |
J Am Coll Radiol
December 2024
Vice Chair for Radiology, Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts; Co-Chair, RSNA Health Equity Committee; Associate Editor, Journal of the American College of Radiology.
Purpose: The aim of this study was to assess how pandemic-related health concerns and discrimination affected cancer screenings among Asian American women (AAW).
Methods: A two-phase explanatory mixed-methods study was conducted. In phase 1, a survey was distributed among AAW eligible for lung, breast, or colorectal cancer screening to assess delays during the pandemic, concerns about contracting coronavirus disease 2019 (COVID-19), barriers to care, and experiences of discrimination.
Viruses
December 2024
HUN-REN Veterinary Medical Research Institute, 1143 Budapest, Hungary.
To address a gap in our understanding of viral infections in epidemiologically important rat species, we aimed to detect DNA viruses from the tissues of free-ranging rat populations in Hungary. DNA viruses were identified from the parenchymal organs of 230 and , using family-specific pan-PCR assays followed by sequencing of the PCR products. Adeno-, herpes-, circo-, and polyomaviruses were detected, while irido-, pox-, and dependoparvoviruses were not.
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December 2024
Department of Infectious Diseases, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, 413 46 Gothenburg, Sweden.
The tick-borne encephalitis virus is a pathogen endemic to northern Europe and Asia, transmitted through bites from infected ticks. It is a member of the family and possesses a positive-sense, single-stranded RNA genome encoding a polypeptide that is processed into seven non-structural and three structural proteins, including the envelope (E) protein. The glycosylation of the E protein, involving a single N-linked glycan at position N154, plays a critical role in viral infectivity and pathogenesis.
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December 2024
Institute for Integrative Systems Biology (I2SysBio), Universitat de València and Consejo Superior de Investigaciones Científicas, 46980 València, Spain.
Viromics studies are allowing us to understand not only the enormous diversity of the virosphere, but also the potential threat posed by the emerging viruses. Regarding the latter, the main concern lies in monitoring the presence of RNA viruses, but the zoonotic potential of some DNA viruses, on which we have focused in the present study, should also be highlighted. For this purpose, we analyzed 160 fecal samples from 14 species of small terrestrial mammals, 9 of them belonging to the order .
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November 2024
Centre for Biological and Health Sciences, Pará State University, Belém 66087-662, PA, Brazil.
The biting midges Latreille, 1809 (Diptera: Ceratopogonidae) is highly relevant to epidemiology and public health, as it includes species that are potential vectors of human and animal arboviruses. The aim of this study was to investigate the presence of RNA viruses in species of the genus collected in the Carajás mining complex in the state of Pará. The biting midges were collected in the municipalities of Canaã dos Carajás, Curionópolis and Marabá and morphologically identified.
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