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Reversible Dilated Cardiomyopathy Associated With Herpes Simplex Virus Infection: A Case Report.
Cureus
December 2024
Internal Medicine, Hospital Vila Franca de Xira, Vila Franca de Xira, PRT.
Dilated cardiomyopathy (DCM) is a serious condition often leading to acute heart failure (HF), with diverse etiologies including viral myocarditis. This report details a case of reversible DCM in a 34-year-old male who presented with symptoms of acute HF. Diagnostic workup revealed biventricular dilation with severe systolic dysfunction and serology confirming herpes simplex virus infection.
View Article and Find Full Text PDFTalc-induced pericardial granulomatosis after recurrent pleurodesis: a rare cause of incessant pericarditis-case report.
Eur Heart J Case Rep
December 2024
Thoracic Surgery Department, Ramón y Cajal University Hospital, Madrid, Spain.
Article Synopsis
- Management of relapsing pericarditis can be challenging, especially when patients do not respond to typical medical treatments, making surgical options like pericardiectomy a potential solution.
- The case involves a 41-year-old woman who experienced persistent acute pericarditis after talc pleurodesis for recurrent pneumothorax and did not benefit from several medications, ultimately requiring surgery.
- Following an anterior pericardiectomy, where foreign body granulomas were found, the patient recovered without pain, indicating that surgical intervention can be effective for this condition, although talc-induced pericarditis is not commonly documented in medical literature.
Inflammatory biomarker analysis confirms reduced disease severity in heterozygous patients with familial Mediterranean fever.
RMD Open
November 2024
Pediatric Rheumatology and Immunology, University Medicine, Albert-Schweitzer-Campus 1, Munster, Germany.
Article Synopsis
- Familial Mediterranean fever (FMF) is a genetic condition marked by inflammation episodes, usually treated with colchicine to prevent complications like amyloid A amyloidosis, but its necessity for heterozygous patients is debated.* -
- A study analyzed 747 FMF patients' demographic and inflammatory biomarker data, revealing that heterozygous patients generally exhibited lower inflammatory markers compared to those with more severe genetic variants.* -
- The findings suggest that certain biomarkers (S100A8/A9 and S100A12) can indicate disease activity, and some heterozygous patients may be eligible to safely stop colchicine treatment.*
Alterations of Hepatic Lipidome Occur in a Gouty Model: A Shotgun Lipidomics Study.
J Inflamm Res
October 2024
College of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310053, People's Republic of China.
Background: Liver injury, such as nonalcoholic fatty liver disease, is a common symptom observed in patients with gout/hyperuricaemia. However, the exact mechanisms are still unclear. There is ongoing controversy about whether representative agents like colchicine and febuxostat, commonly used to manage gout, could also help prevent the liver injury.
View Article and Find Full Text PDFRhabdomyolysis associated with concomitant use of colchicine and statins in the real world: identifying the likelihood of drug-drug interactions through the FDA adverse event reporting system.
Front Pharmacol
September 2024
Department of Pharmacy, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China.
Article Synopsis
- * Using data from the FDA Adverse Event Reporting System, the researchers found 255 reports of rhabdomyolysis linked to the combination of these drugs, indicating a potential drug-drug interaction.
- * The results suggested an increased risk of rhabdomyolysis, especially with atorvastatin and rosuvastatin, urging healthcare professionals to monitor patients closely when prescribing these medications together.
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