Fine needle aspiration cytology of primary isolated splenic Blastomyces dermatitidis. A case report.

Background: Blastomyces dermatitidis is a dimorphic fungus; its usual port of entry is the lung. Although any organ system can be secondarily involved, non-pulmonary sites of primary infection have been reported.

Case: This is the first reported case of primary isolated splenic B dermatitidis. The diagnostic value of fine needle aspiration cytology was examined by comparing it with the only previously reported case of primary (not isolated) splenic B dermatitidis.

Conclusion: In patients with splenic involvement by B dermatitidis, cytologic evaluation can be prompt and diagnostic. FNA biopsy in patients with splenomegaly is safe and well tolerated.