AI Article Synopsis
- In infertile men with clinical varicoceles, both testicles tend to be smaller than normal and sperm analysis shows a high percentage of immature and poorly motile sperm.
- Serotonin has been found in the plasma of these patients, and it's believed to negatively impact sperm motility.
- Surgical intervention for bilateral varicoceles can enhance fertility potential, making it a recommended treatment option.
Article Abstract
In infertile men, clinical varicoceles most often occur bilaterally. In our experience with these patients, both testicles are smaller than normal. We find more than 25% to 35% immature and tapered sperm in in the ejaculum of these men, and the motility of the sperm is usually low. We have found serotonin in the plasma of the varicoceles, and believe this biogenic amine is responsible for the poor sperm motility. We now agree that a subset of neuroendocrine cells in the prostate secrete serotonin. Bilateral varicocele surgery can improve the patient's fertility potential, and we advocate surgical treatment.
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| http://dx.doi.org/10.1111/j.1442-2042.1998.tb00256.x | DOI Listing |
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