A variant of liquid-phase radioimmunoassay (RIA) with murine monoclonal antibodies E7(B2-1) to human alpha-fetoprotein (AFP) is described. AFP levels were measured by RIA with a commercial DIAplus kit in the sera of patients with germinogenic tumors and of pregnant women.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Association and interaction of the MC4R rs17782313 polymorphism with plasma ghrelin, GLP-1, cortisol, food intake and eating behaviors in overweight/obese Iranian adults.
BMC Endocr Disord
September 2022
Department of Cellular - Molecular Nutrition, School of Nutrition Sciences and Dietetics, Tehran University of Medical Sciences, PO Box: 14155-6447, Tehran, Iran.
Background: Recent studies have shown that obesity is largely influenced by heredity and created by the interactions between several genes and environmental and behavioral factors. This study aimed to examine association between variant rs17782313 near melanocortin-4 receptor (MC4R) gene and behavioral and hormonal factors then evaluated interactions between variant MC4R rs17782313 with behavioral and hormonal factors on obesity.
Methods: This cross-sectional study included 403 subjects, overweight and/or obesity, aged 20-50 years from Iran.
WT1 suppresses follicle-stimulating hormone-induced progesterone secretion by regulating ERK1/2 pathway in chicken preovulatory granulosa cells.
Gene
February 2022
College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction, Ministry of Education Huazhong Agricultural University, Wuhan 430070, China. Electronic address:
Multiple Wilms tumor gene 1 (WT1) splicing variants are expressed in mammals, and these variants regulate tumorigenesis and mediate the development of multiple tissues and organs, including gonads. However, WT1 splicing variants (+KTS or -KTS) are expressed in only two nonmammalian vertebrates, and unexpectedly, their functions in chicken ovaries remain elusive. Progesterone (P4) secreted by chicken granulosa cells (GCs) participates in various physiological processes and plays an important role in maintaining reproductive performance.
View Article and Find Full Text PDFSequential Social Exclusion in a Novel Cyberball Paradigm Leads to Reduced Behavioral Repair and Plasma Oxytocin in Borderline Personality Disorder.
J Pers Disord
February 2022
Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Germany.
Patients with borderline personality disorder (BPD) show interpersonal deficits, and altered emotional and oxytocin (OT) responses to social exclusion (Cyberball). In order to extend previous findings, this study applies a novel Cyberball variant. Nineteen BPD patients and 56 healthy controls (HC) played Cyberball for 2 minutes of inclusion, 5 minutes of partial exclusion by one of two co-players, and 2 minutes total exclusion by both.
View Article and Find Full Text PDFIn1-Ghrelin Splicing Variant as a Key Element in the Pathophysiological Association Between Obesity and Prostate Cancer.
J Clin Endocrinol Metab
November 2021
Maimonides Institute of Biomedical Research of Cordoba (IMIBIC), Cordoba, Spain.
Article Synopsis
- * Researchers investigated the relationship between urine In1-ghrelin levels and various metabolic factors (like obesity and diabetes) to determine its clinical relevance in assessing PCa risk among patients with ambiguous PSA results.
- * The findings show that In1-ghrelin levels are significantly higher in PCa patients, correlating with increased cancer risk and aggressiveness, and enhancing the diagnostic accuracy of existing clinical models.
sequence variant and elevated gene expression are associated with type 1 diabetes in Polish children.
Cent Eur J Immunol
January 2020
Department of Pediatric Diabetes and Obesity, Poznan University of Medical Sciences, Poznan, Poland.
Introduction: Type 1 diabetes (T1D) is caused by the autoimmune destruction of pancreatic β cells, resulting from coincident genetic predisposition and some environmental triggers. Signal transducer and activator of transcription 4 (STAT4) gene encodes a transcription factor, which promotes Th1 cell differentiation, interferon γ production, and development of Th17 cells. Polymorphisms of STAT4 are associated with several autoimmune conditions, while studies in T1D provided inconsistent results.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!