I-123-MIBG scintigraphy has become a standard imaging technique in the detection of neuroendocrine or neurocrest derived tumors, especially neuroblastoma and pheochromocytoma. We report on a positive I-123-MIBG uptake in a pediatric osteosarcoma patient and demonstrate, that unusual results still occur with this established imaging method.
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Transformation of a Nonfunctional Paraganglioma With I-123 MIBG Scintigraphy Correlation: A Case Report.
Medicine (Baltimore)
January 2016
From the Department of Radiology (EAD, JC, HD, DB, JS); and Department of Pathology, Harbor-UCLA Medical Center, Torrance, CA (HS).
A 35-year-old woman presenting with abdominal pain was found to have mildly elevated catecholamine levels and a retroperitoneal mass. The patient underwent a negative I-123 MIBG scintigraphy scan and a nondiagnostic fine needle aspiration. Eleven years later the patient presented with a hypertensive emergency and markedly elevated catecholamine levels.
View Article and Find Full Text PDFI-123 MIBG scintigraphy and 68Ga-DOTANOC PET/CT negative but F-18 DOPA PET/CT positive pheochromocytoma: a case report.
Clin Nucl Med
February 2011
Unità Operativa di Medicina Nucleare, Policlinico S. Orsola-Malpighi, Bologna, Italy.
We observed a 34-year-old man who was incidentally found to have an adrenal mass during surgical follow-up for perforated ulcer. The patient was subjected to I-123 MIBG scintigraphy, 68Ga-DOTANOC PET/CT, and F-18 DOPA PET/CT. Only F-18 DOPA PET/CT showed evidence of an avid adrenal mass.
View Article and Find Full Text PDFThe reversibility of cardiac neuronal function after removal of a pheochromocytoma: an I-123 MIBG Scintigraphic Study.
Clin Nucl Med
July 1999
Nuclear Medicine, CHU Côte de Nacre, Caen, France.
Purpose: Twelve patients with proved pheochromocytoma evaluated in our institution between 1991 and 1997 are described.
Methods: The patients' urinary excretion rates and their metabolites (vanylmandelic acid and metanephrines) were significantly greater than normal before surgery. Echocardiography showed normal left ventricular ejection fractions (72% +/- 8%).
False-positive diagnosis of adrenal pheochromocytoma on iodine-123-MIBG scan.
J Endocrinol Invest
December 1998
Istituto di 2a Clinica Medica, Università degli Studi di Roma, La Sapienza, Italy.
1-123 metaiodobenzylguanidine (1-123 MIBG) scintigraphy is known for its high specificity in detecting pheochromocytoma and other tumors of neural crest origin. In this rare case report, we describe a definite adrenocortical adenoma that demonstrated false-positive uptake at I-123 MIBG scintigraphy and a remarkable accumulation of 75-SE-6-beta-selenomethyl-norcholesterol.
View Article and Find Full Text PDFPositive I-123-MIBG-scintigraphy in osteosarcoma.
Nuklearmedizin
March 1998
Department of Pediatrics, University of Erlangen-Nürnberg, Germany.
I-123-MIBG scintigraphy has become a standard imaging technique in the detection of neuroendocrine or neurocrest derived tumors, especially neuroblastoma and pheochromocytoma. We report on a positive I-123-MIBG uptake in a pediatric osteosarcoma patient and demonstrate, that unusual results still occur with this established imaging method.
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