The influence of oxidized low density lipoprotein (LDL) on a human endothelial cell monolayer was examined. The resulting contraction of the oxidized LDL-damaged endothelial cells lets intercellular spaces become enlarged and therefore visible via light microscopy. Electron microscopy reveals that the structural damage facilitates thrombocyte adhesion and formation of microthrombi. Oxidized LDL appears to play a pivotal role in initiating and deteriorating thromboembolic complications.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/(sici)1096-8652(199804)57:4<341::aid-ajh13>3.0.co;2-b | DOI Listing |
Publication Analysis
Top Keywords
oxidized ldl
8
endothelial cell
8
cell monolayer
8
thrombocyte adhesion
8
oxidized
4
ldl damages
4
damages endothelial
4
monolayer promotes
4
promotes thrombocyte
4
adhesion influence
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!