We report a case of idiopathic hypertrophic cranial pachymeningitis in which a high accumulation of thallium-201 was observed on an early single-photon emission CT (SPECT) scan. The patient's symptoms initially improved with steroid therapy but recurred repeatedly. MR images failed to show any change with treatment; however, thallium-201 uptake correlated closely with the fluctuation of symptoms. 201Tl-SPECT was therefore useful in identifying inflammatory activity that was not detected by MR imaging.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8338252PMC

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