Pheohyphomycoses are an uncommon diverse group of dematiaceous fungi present in soil and plant material and are potential pathogens. We report the case of a 45-year-old white Hispanic woman who presented with a hard round cyst on the dorsum of her right foot caused by a traumatic implantation of a piece of wood thirty-five years earlier. The cyst was surgically excised and the patient empirically treated with a two-month course of oral itraconazole. To our knowledge, this represents a case of the longest-lived asymptomatic pheohyphomycotic cyst in an immunocompetent person ever reported. The clinical manifestations, treatment options, and disease course are reviewed.
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Int J Surg Pathol
January 2025
Department of Pathology, Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Trivandrum, Kerala, India.
Phaeohyphomycotic agents causing central nervous system (CNS) infection is rare and is known to affect immunocompetent individuals. We present a patient with a CNS phaeohyphomycotic abscess that had developed within a temporal lobe glioma. Magnetic resonance imaging (MRI) performed two months prior to the surgery showed only the presence of a neoplasm.
View Article and Find Full Text PDFIDCases
December 2024
Department of Pathology, Sri Venkateshwaraa medical college hospital and research centre, Ariyur, Puducherry, India.
Med Mycol Case Rep
June 2024
Medical Mycology Laboratory, Instituto Costarricense de Investigación y Enseñanza en Nutrición y Salud, Cartago, Costa Rica.
is a genus of dematiaceous fungi that rarely causes human infections. We describe a case of subcutaneous infection in a 70-year-old diabetic man with lesions on the dorsum of the one foot. The agent was isolated, and for the final identification we performed matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) and DNA sequencing.
View Article and Find Full Text PDFAutops Case Rep
January 2023
Post Graduate Institute of Medical Education and Research, Department of General Surgery, Chandigarh, India.
J Am Podiatr Med Assoc
September 2022
‡Pathology Laboratory, Foot and Ankle Specialists of the Mid-Atlantic, LLC, Rockville MD.
Phaeohyphomycosis is a spectrum of subcutaneous and systemic infections caused by a variety of dematiaceous fungi. It is an opportunistic disease with an increased incidence in immunocompromised patients. We report a case of a pedal phaeohyphomycotic cyst in an immunocompetent adult male immigrant with the goal of highlighting its clinical presentation, diagnosis, and optimal treatment.
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