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Effects of balis-2 on exploratory activity in the open field and elevated plus-maze, attention to sensory stimuli of different modalities, elaboration and retention of conditioned reflexes with food reinforcement, were studied in rats under stress. Prolonged treatment of rats with balis-2 seems to normalise integrative activity and metabolism of serotonine and dopamine in the animal brain.

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Baliz-2, a new antibacterial drug, was used to prevent nasopharyngeal infection before and after uranoplasty in 25 children with palatal clefts. Sanitation effect of the drug was revealed; the incidence of postoperative inflammatory complications was reduced.

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On the basis of comparative analysis of the results of treatment of 201 patient with diabetes mellitus and purulent wounds of the soft tissues (conventional methods of treatment were employed in 66, with local use of the Baliz-2 preparation--in 82, use of the Baliz-2 preparation with simultaneous performance of transplantation of the pancreatic islet cells of the newborn pigs--in 53), a high effectiveness of influence upon the reparative processes of an organism of the pancreatic islet cells culture xenotransplantation has been proved. The action of a transplant retains after healing of the purulent wounds.

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Examinations of 137 patients with inflammatory diseases of the maxillofacial area and neck, treated with baliz-2, have shown that this agent is characterized by a manifest antibacterial action on the wound microflora, helps thinning the purulent exudate, and accelerates detachment of the necrotic mass. No cases of local irritation were recorded.

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