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A Case of Severe Hypocalcemia During JAK1/2 Inhibitor Therapy for Myelofibrosis in a Patient with Liver Cirrhosis.
Intern Med
January 2025
Department of Internal Medicine 1, Shimane University Faculty of Medicine, Japan.
We herein report a 56-year-old man with severe hypocalcemia during ruxolitinib therapy for myelofibrosis transitioning from JAK2 mutation-positive polycythemia vera. Blood transfusions were administered every one to two weeks for ruxolitinib-induced anemia. Blood tests revealed hypocalcemia with low TRACP-5b, 25-hydroxyvitamin D (25 (OH) D), and 1,25-dihydroxyvitamin D (1,25 (OH) D) levels within the lower reference range.
View Article and Find Full Text PDFIntralesional Bleomycin for Orbital Venolymphatic Malformation.
Cureus
December 2024
Department of Radiology, Hospital Kuala Lumpur, Kuala Lumpur, MYS.
This retrospective case series evaluates the use of intralesional bleomycin injections in treating orbital venolymphatic malformations (OVLM). Three patients, a 7-year-old girl, a 37-year-old woman, and a 56-year-old man, presented with OVLM where the first two were recurrent cases with a history of failed sclerotherapy. All patients received multiple doses of intralesional bleomycin injections, resulting in significant reductions in lesion size, decreased proptosis, and pain relief.
View Article and Find Full Text PDFSuccessful Treatment of an Atypical Presentation of Disseminated Retroperitoneal Seminoma: A Case Report.
HCA Healthc J Med
December 2024
Menorah Medical Center, Overland Park, KS.
Background: Testicular seminoma is the most common malignant tumor of the testis. It occurs at a rate of 5 per 100 000 men, primarily between the ages of 15 to 34. While seminomas typically occur in the testis, other primary sites include the mediastinum, the retroperitoneum, or other extra-gonadal sites.
View Article and Find Full Text PDFElectroconvulsive Therapy-Induced Mania in Bipolar Disorder: A Case Report.
Cureus
December 2024
Psychiatry, Psychiatrisch Ziekenhuis Asster, Sint-Truiden, BEL.
Electroconvulsive therapy (ECT) is widely recognized as a safe and effective intervention for treating severe affective episodes in patients with bipolar disorder. However, it can sometimes precipitate unexpected manic phases in patients treated for a depressive episode, a phenomenon known as ECT-induced mania. While this occurrence is recognized, it remains poorly understood and minimally addressed in the literature.
View Article and Find Full Text PDFIdentification and treatment of -induced diabetic foot ulcer: a case report and microbiome analysis.
Front Med (Lausanne)
December 2024
Department of Clinical Laboratory, Sir Run Run Hospital, Nanjing Medical University, Nanjing, China.
Article Synopsis
- Diabetic foot ulcers (DFUs) can lead to severe complications like amputation if not treated promptly, often due to delays in care.
- A 56-year-old patient experienced a DFU linked to a bacterial infection from poultry exposure, requiring multiple debridement surgeries and targeted antibiotic treatment.
- Effective management of DFUs involves adjusting antibiotic therapies based on identified pathogens to reduce mortality and prevent irreversible amputations.
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