We come up the case of a six and a half year old girl suffering from right unilateral perisylvian cortical dysplasia who present left spastic hemiparesia, mirror movements and language disorder. She made her epileptic debut at the age of four and a half with myoclonic absences which responded to valproate treatment. At the age of five she began with biopercular status epilepticus shown as pseudobulbar palsy as diffusion of discharges from the dysplasia localization to the contralateral one. These episodes look places with variable duration from one hour to one month and finished after medical treatment or spontaneously. At the present a pseudobulbar palsy persistence and a bilateralization in the symptoms is observed.
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Seizure
October 2024
Epilepsy Center, Neurological Institute, Cleveland Clinic, 9500 Euclid Avenue, Desk S60, Cleveland, OH 44195, United States. Electronic address:
Cureus
April 2023
Neurology, Sree Mookambika Institute of Medical Science, Trivandrum, IND.
Foix-Chavany-Marie syndrome (FCMS) presents with anarthria and bilateral (B/L) central facio-linguo-velo-pharyngo-masticatory paralysis with "autonomic voluntary dissociation." The most common cause of FCMS is cerebrovascular disease, while rarer causes include central nervous system infection, developmental disorders, epilepsy, and neurodegenerative disorders. Even though this syndrome is also referred to as (B/L) anterior operculum syndrome, patients with lesion in sites other than (B/L) opercular regions also can develop the syndrome.
View Article and Find Full Text PDFEpilepsy Behav
June 2023
Comprehensive Epilepsy Program, Department of Neurology, University of Virginia, Charlottesville, VA, USA. Electronic address:
Background And Objectives: Neuropsychological research on mesial temporal lobe epilepsy (MTLE) often highlights material-specific memory deficits, but a lesion-focused model may not accurately reflect the underlying networks that support episodic memory in these patients. Our study evaluated the pathophysiology behind verbal learning/memory deficits as revealed by hypometabolism quantified through 18-fluorodeoxyglucose positron emission tomography (FDG-PET).
Methods: This retrospective study included thirty presurgical patients with intractable unilateral MTLE who underwent interictal FDG-PET and verbal memory assessment (12 females, mean age: 38.
Neurol Neuroimmunol Neuroinflamm
July 2023
From the Division of Pediatric Neurology and Developmental Neuroscience (A.J.S., V.K., K.S.F.), Department of Pediatrics; Department of Radiology (N.K.D., S.F.K.); and Department of Pediatrics (E.M.), Section of Rheumatology, Baylor College of Medicine and Texas Children's Hospital.
Background And Objectives: Anti-NMDA receptor autoimmune encephalitis (NMDAR AE) is an autoantibody-mediated disorder characterized by seizures, neuropsychiatric symptoms, movement disorder, and focal neurologic deficits. Conventionally defined broadly as an inflammatory brain disease, the heterotopic localization is rarely discussed in children. Imaging findings are often nonspecific, and there are no early biomarkers of disease other than the presence of anti-NMDAR antibodies.
View Article and Find Full Text PDFEpileptic Disord
February 2023
Department of Neurology, Sanbo Brain Hospital, Capital Medical University, Beijing, 100093, China.
Objective: To study the semiology characteristics of motor seizures of axial and shoulder girdle muscles (ASMs) by stereoelectroencephalography (SEEG) and its value in determining location of epileptogenic zone.
Methods: A total of 598 patients underwent SEEG assessment in Sanbo Brain Hospital were reviewed; 65 patients with ASMs selected. Thirteen semiology feature items were extracted according to the location and symmetry of involved axial muscles, direction of movement, etc.
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