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| http://dx.doi.org/10.1007/BF03405791 | DOI Listing |
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Influence of Environmental Factors on the Aboveground Biomass of Mature and Postmining Forests in Chocó.
Life (Basel)
January 2025
Department of Agroforestry Sciences, Institute of Sustainable Forest Management Research UVa_INIA, E.T.S. (Higher Technical School) of Agrarian Engineering of Palencia, University of Valladolid, 34004 Palencia, Spain.
Environmental factors control the accumulation of aboveground biomass (AB) in tropical forests, along with the role of AB in climate change mitigation. As such, the objective of this study was to evaluate the influence of factors such as forest type, succession, abundance of individuals, species richness, height, diameter, texture, and soil nutrient levels on the AB in mature and postmining forests in Chocó, Colombia. Five plots each were set up in primary and postmining forests with 15 and 30 years of regeneration, in which the amount of AB was measured and related to the environmental factors.
View Article and Find Full Text PDFMultiscale footprints reveal the organization of cis-regulatory elements.
Nature
January 2025
Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Cis-regulatory elements (CREs) control gene expression and are dynamic in their structure and function, reflecting changes in the composition of diverse effector proteins over time. However, methods for measuring the organization of effector proteins at CREs across the genome are limited, hampering efforts to connect CRE structure to their function in cell fate and disease. Here we developed PRINT, a computational method that identifies footprints of DNA-protein interactions from bulk and single-cell chromatin accessibility data across multiple scales of protein size.
View Article and Find Full Text PDFElectro-tactile modulation of muscle activation and intermuscular coordination in the human upper extremity.
Sci Rep
January 2025
Department of Biomedical Engineering, University of Houston, 3517 Cullen Blvd, SERC Room 2011, Houston, TX, 77204-5060, USA.
Electro-tactile stimulation (ETS) can be a promising aid in augmenting sensation for those with sensory deficits. Although applications of ETS have been explored, the impact of ETS on the underlying strategies of neuromuscular coordination remains largely unexplored. We investigated how ETS, alone or in the presence of mechano-tactile environment change, modulated the electromyogram (EMG) of individual muscles during force control and how the stimulation modulated the attributes of intermuscular coordination, assessed by muscle synergy analysis, in human upper extremities.
View Article and Find Full Text PDFUnderstanding the stroke burden in Saudi Arabia: Trends from 1990 to 2019 and forecasting through time series analysis.
Neurosciences (Riyadh)
January 2025
From the Department of Family and Community Medicine (Mahfouz, Ghazy), College of Medicine, King Khalid University, Abha, Kingdom of Saudi Arabia, from Alexandria Directorate of Health Affairs (Abdelmoneim), Egyptian Ministry of Health and Population, Alexandria, Department of Public Health and Community Medicine (Abdu), Faculty of Medicine, Mansoura University, Mansoura, from Public Health and Community Medicine (AboElela, Shiba), Faculty of Medicine for Girls, Al-Azhar University, Cairo, Neuroscience Center (Alhazzani), King Faisal Specialist Hospital and Research Center, Riyadh, Kingdom of Saudi Arabia.
Objectives: To describe age-standardized incidence and disability-adjusted life years (DALYs) of ischemic stroke (IS), intracerebral hemorrhage (ICH), and subarachnoid hemorrhage (SAH) in the Kingdom of Saudi Arabia (KSA) from 1990 to 2019 and forecast these variables using the Global Burden of Diseases (GBD) data over the next years (2020-2030).
Methods: Poisson regression models were employed to identify significant changes in incidence rate ratios (IRRs) and DALY rates for different stroke types. For time series models, the autoregressive integrated moving average (ARIMA) and exponential smoothing state space (ETS) models were used for forecasting.
Open-label evaluation of oral trehalose in patients with neuronal ceroid lipofuscinoses.
J Neurol
January 2025
IRCCS Stella Maris Foundation, Via Dei Giacinti 2, 56128, Pisa, Italy.
The neuronal ceroid lipofuscinoses (NCLs) are incurable pediatric neurodegenerative diseases characterized by accumulation of lysosomal material and dysregulation of autophagy. Given the promising results of treatment with trehalose, an autophagy inducer, in cell and animal models of NCL, we conducted an open-label, non-placebo-controlled, non-randomized 12-month prospective study in NCL patients receiving oral trehalose (4 g/day). All were treated with a commercially available formulation for 6 months, followed by a 6-month washout.
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