Parkinson's disease is one of the most frequent chronic diseases. Prevalence varies widely across geographic areas and studies. Although geographic variation could be produced by environmental factors, most of the studies have different methodology, and the diagnostic criteria which have been used are not homogeneous. Population-based door-to-door studies are an accurate method for determining disease frequency in a community. This paper analyses diagnostic criteria in Parkinson's disease and its influence on the prevalence estimated by this type of studies.
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