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Traction-assisted endoscopic ultrasound-guided fine-needle biopsy using the clip-with-thread method for small gastric subepithelial lesions: Randomized controlled trial (with video).
Dig Endosc
January 2025
Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Objectives: Endoscopic ultrasound-guided fine-needle aspiration/biopsy (EUS-FNA/B) is the gold standard for diagnosing gastric subepithelial lesions (SELs), but diagnosing lesions smaller than 20 mm remains challenging. We developed traction-assisted EUS-FNB (TA-EUS-FNB) using the clip-with-thread method to enhance diagnostic accuracy by stabilizing the lesion and providing counter-traction for easier needle access. This study evaluates the effectiveness of TA-EUS-FNB in diagnosing small gastric SELs.
View Article and Find Full Text PDF[Pathological diagnosis of solid pancreatic lesions with endoscopic ultrasound-guided fine needle aspiration: a series study of 311 cases].
Zhonghua Bing Li Xue Za Zhi
January 2025
Department of Pathology, the Second Hospital of Hebei Medical University, Shijiazhuang050000, China.
To investigate the combined application of cytology, cell block histology and immunohistochemistry to improve the diagnostic accuracy of solid pancreatic lesions in endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) samples. The pathological data of EUS-FNA in 311 cases of solid pancreatic lesions submitted to the Second Hospital of Hebei Medical University, Shijiazhuang, China from May 2019 to September 2023 were retrospectively analyzed. The cases included pancreatic ductal adenocarcinoma (PDAC, 172 cases), solid pseudopapillary neoplasm (SPN, 12 cases), neuroendocrine tumors (PNET, 14 cases) and chronic pancreatitis (113 cases).
View Article and Find Full Text PDFFortuitous discovery of a superior and posterior pancreaticoduodenal artery originating from the right branch of the hepatic artery during cadaver dissection.
Morphologie
January 2025
Department of Digestive Surgery, Amiens Picardy University Hospital, 1, rondpoint du Pr-Cabrol, 80054 Amiens, France; Simplifying Care for Complex Patients, UR-UPJV 7518 SSPC, Clinical Research Unit, University of Picardie Jules-Verne, Amiens, France.
Introduction: The duodeno-pancreatic region is a highly vascularized area. The superior and posterior pancreaticoduodenal artery is a vessel primarily originating from the gastroduodenal artery. It exhibits rare anatomical variations, such as its emergence from the right branch of the hepatic artery, which we fortuitously identified during a cadaver dissection.
View Article and Find Full Text PDFSolid pseudopapillary neoplasm of the pancreas in a 54-year-old woman: A case report and the literature analysis.
Pathol Res Pract
December 2024
Dnipro State Medical University, Dnipro 49044, Ukraine.
Introduction: Solid pseudopapillary neoplasm (SPN) is a rare pancreatic tumor typically occurring in young females. This case presents an instance of SPN in a 54-year-old Caucasian female, highlighting atypical age of onset and providing new insights into the tumor's clinical and histopathological diversity.
Case Report: A 54-year-old female with no significant past medical history presented with upper abdominal discomfort and weakness.
Hippo-YAP signaling alleviates copper-induced mitochondrial dysfunction and oxidative damage via the ATOX1-PPA2 pathway.
Int J Biol Macromol
December 2024
Laboratory of Animal Developmental Biology, College of Life Science, Northeast Forestry University, Harbin 150040, China. Electronic address:
Article Synopsis
- Hippo signaling is important for cellular responses to stress, but its role in copper (Cu) stress is not well understood.
- In sheep pancreas and organoids exposed to high Cu, Hippo-YAP signaling was abnormally activated, leading to oxidative stress and mitochondrial damage.
- Inhibiting Hippo signaling or increasing YAP levels improved mitochondrial function and copper balance, showing that YAP and ATOX1 work together to protect cells from Cu stress and restore their antioxidant capacity.
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