Pressure sores are a major problem frequently encountered by persons who use wheelchairs. Custom seat design, including contoured seating and various modular seating devices, has become an important option for pressure relief, especially when the market size is small and the variations of individual needs and requirements are large. An alternative approach in custom seating design for pressure relief is proposed in this paper. Holes were drilled in foam cushions to lower their supporting properties, particularly at the high pressure areas. This technique is evaluated systematically in this article. The scope of this study included: 1) a comparison of the foam material properties before and after such modifications, and 2) an evaluation of the static and dynamic degradation behaviors of the foams before and after modifications. It was found that the compression load (C-L) of the foam could be reduced by up to 46% using this simple drilling technique, while the material removed was only up to 28% by volume. It was also found that this approach would not significantly compromise the static and dynamic degradation behaviors of the foam; that is, such modification apparently did not dramatically shorten the lifespan of the foam material. Simple hole-drilling seems to be an effective approach to altering the supportive properties of foam cushions for pressure relief.
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Sci Rep
January 2025
School of Civil Engineering and Architecture, Anhui University of Science and Technology, Huainan, 232001, Anhui, China.
To investigate the changes in the strength and deformation of the blast load-damaged sandstone roof plate under cyclic loading and unloading conditions at different confining pressures, a triaxial loading device was used to carry out graded cyclic unloading tests on specimens with different degrees of damage, and the test results were summarized. The effects of blast-load-induced damage, confining pressure and loading stage on the strength, cohesion, internal friction angle, residual strain and volumetric strain were analyzed. (1) Compared with that of the undamaged specimen at a confining pressure of 0 MPa, the peak stress reductions in the vibration-damaged and blast-damaged specimens were 4.
View Article and Find Full Text PDFSci Rep
January 2025
College of Water Conservancy and Civil Engineering, Xinjiang Agricultural University, Urumqi, China.
Cureus
November 2024
Anesthesiology and Pain Medicine, Harborview Medical Center, Seattle, USA.
Prompt emergence from general anesthesia is crucial after neurosurgical procedures, such as craniotomies, to facilitate timely neurological evaluation for identification of intraoperative complications. Delayed emergence can be caused by residual anesthetics, metabolic imbalances, and intracranial pathology, for which an eye examination can provide early diagnostic clues. The sunset sign (or setting sun sign), characterized by a downward deviation of the eyes, can be an early indicator of raised intracranial pressure (ICP) or midbrain compression, as is commonly observed in states of hydrocephalus or periaqueductal or tectal plate dysfunction.
View Article and Find Full Text PDFBrain Behav Immun
December 2024
Wolfson Sensory, Pain and Regeneration Centre, King's College London, Guy's Campus, London Bridge, London SE1 1UL, UK. Electronic address:
Angiotensin II is well known to have an important influence on blood pressure, mediated via the angiotensin II type 1 receptor (AT1R), and more recent studies have shown that angiotensin II may play an important additional role in eliciting pain via a distinct action at the angiotensin II type 2 receptor (AT2R). Signalling pathways that link activation of AT2R to a sensation of pain are, however, incompletely understood. Here we use rodent inflammatory pain models to confirm that selective activation of AT2R triggers aversive responses, and that these are abolished by either antagonism or genetic deletion of AT2R.
View Article and Find Full Text PDFCureus
November 2024
Integrated Clinical Education Center, Kyoto University Hospital, Kyoto, JPN.
This case report highlights the diagnostic process for posterior cutaneous nerve entrapment syndrome (POCNES) in an older adult female patient, with an emphasis on using video demonstrations to guide clinicians. POCNES should be diagnosed based on a combination of specific clinical features, including localized back pain accompanied by pinpoint tenderness lateral to the spinous process, cutaneous sensory abnormalities over the area of pain, severe pain response to pressure on the tender point, and normal clinical and imaging findings. This case demonstrates how these criteria were identified via a thorough physical examination captured on video to provide a visual guide for clinicians.
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