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The role of IFN-γ/CXCL10 axis in Mycoplasma pneumonia infection.
Sci Rep
January 2025
Department of Respiratory Medicine, Children's Hospital of Soochow University, Suzhou, China.
Mycoplasma pneumoniae caused lower respiratory tract infection in children and can exacerbate these infections through the production of various inflammatory factors, with chemokines playing a key role. However, the pathogenesis of this infection is complicated and thus has not been thoroughly studied. We clarified that cytokine expression levels were analyzed in both peripheral blood and bronchoalveolar lavage fluid (BALF), and in vitro assays were conducted using THP-1 macrophages.
View Article and Find Full Text PDFFatal interactions: pneumonia in bighorn lambs following experimental exposure to carriers of .
J Clin Microbiol
January 2025
Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington, USA.
We hypothesized that bighorn sheep ewes with chronic nasal carriage are the source of infection that results in fatal lamb pneumonia. We tested this hypothesis in captive bighorn ewes at two study facilities over a 5-year period, by identifying carrier ewes and then comparing lamb fates in groups that did (exposed pens) or did not (non-exposed pens) include one or more carrier ewes. Most (23 of 30) lambs born in exposed pens, but none of 11 lambs born in non-exposed pens, contracted fatal pneumonia.
View Article and Find Full Text PDFA serological survey of wild boar in Serbia for and .
Vet Med (Praha)
December 2024
Scientific Institute of Veterinary Medicine of Serbia, Belgrade, Serbia.
and are causative agents of the porcine respiratory disease complex. However, information on the prevalence of these pathogens in wild boars is scarce. This study aimed to investigate the presence of antibodies to and in wild boars in Serbia.
View Article and Find Full Text PDFCharacterization of diffuse lung function in children with pneumonia.
Front Pediatr
January 2025
Pediatric Respiratory Medicine Department, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Background: infection accounts for a high proportion of community-acquired pneumonia and the incidence rate of severe pneumonia (MPP) has increased year by year. This study investigated the changes in lung diffusion function after infection, compared the lung diffusion and ventilation function of children with mild (MMPP) or severe pneumonia (SMPP) infections, and explored their clinical significance.
Objective: To study the changes in pulmonary ventilation and pulmonary diffusion function in children with MPP, and explore their clinical significance.
Mycoplasma pneumoniae (MP) is one of the pathogens that cause community-acquired pneumonia in children. Atopic diseases are also common in children. However, the impact of atopy on Mycoplasma pneumoniae pneumonia (MPP) in children is still unclear.
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