The aim of the study was to investigate the incidence and risk factors for endometrial adenocarcinoma which are associated with abnormal bleeding patterns, overweight, a lower number of deliveries and a later menopause, diabetes mellitus and hypertension. A retrospective study (from 1990 to 1993) of 2887 women with pathological gynecological signs and symptoms was performed. Risk factors such as age, weight, height, Brock index, age of menopause, diabetes mellitus and hypertension, stage and cell type were analysed. The patients were between 38 to 84 years old (average 53.9 +/- 10.2). They were divided into two subgroups: 259 patients below 84 years of age with histologically confirmed neoplasm and 2628 women hospitalised due to gynecological signs and symptoms which were not, however, diagnosed as neoplastic disorders. It was shown that overweight woman in sixth life decade with a lower number of deliveries and a later menopause had a higher risk of endometrial cancer.
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