DNA bending and the curious case of Fos/Jun.

Chem Biol

Division of Pediatric Hematology/Oncology, Dana Farber Cancer Institute and Children's Hospital, Boston, MA 02115, USA.

Published: February 1998

DNA bending has been implicated as an important regulatory mechanism in several processes involving protein-DNA interactions. Various methods for examining intrinsic and protein-induced DNA bending may lead to different conclusions. For the Fos and Jun transcription factors, this has resulted in controversy over whether these factors significantly bend DNA at all.

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http://dx.doi.org/10.1016/s1074-5521(98)90139-9DOI Listing

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