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A 1.5 to 3 Mb microdeletion of chromosome 22q11.2 with loss of multiple genes including histone cell cycle regulator (HIRA) causes 22q11.
View Article and Find Full Text PDF[Prevalence and genetic characteristics of infections among HIV-positive individuals in Jiangxi Province].
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
July 2024
Nanchang Municipal Center for Disease Control and Prevention, Base of National Key Laboratory for the Prevention and Control of Infectious Diseases, Nanchang, Jiangxi 330038, China.
Objective: To investigate the prevalence of infection and the distribution of parasite species and genotypes among HIV-positive individuals in Jiangxi Province.
Methods: HIV-positive individuals' sociodemographic and clinical data were collected from three AIDS designated hospitals in Jiangxi Province from January 2022 to March 2023. Subjects' stool samples were collected, and genomic DNA was extracted from stool samples.
Diagnostic methods and protocols for rapid determination of methicillin resistance in Staphylococcus aureus bloodstream infections: a comparative analysis.
Eur J Clin Microbiol Infect Dis
January 2025
Microbiology and Virology Unit, University Hospital Città Della Salute E Della Scienza Di Torino, Turin, Italy.
Purpose: To evaluate diagnostic performance of four diagnostic methods for rapid determination of methicillin resistance in S. aureus positive blood cultures (BCs).
Methods: Clinical and spiked BCs were subjected to the evaluation of the following methods and protocols: a.
Morphological and molecular characteristics of swine coccidia based on single oocyst isolation.
Parasitol Res
January 2025
College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450046, P.R. China.
Swine coccidiosis is a host-specific protozoan disease caused by Cystoisospora suis and various Eimeria species, leading to diarrhea or subclinical signs in pigs. In this study, 3296 fecal samples from 55 farms across six provinces in China were collected and examined to determine the prevalence and molecular characteristics of swine coccidia. The single oocyst isolation technique (SOIT) and molecular characterization identified nine coccidian species, with an overall infection prevalence of 13.
View Article and Find Full Text PDFRevolutionizing ESCC prognosis: the efficiency of tumor-infiltrating immune cells (TIIC) signature score.
Discov Oncol
January 2025
Second Department of Oncology, The Second Hospital of Hebei Medical University, Shijiazhuang, 050000, China.
Background: Patients suffer from esophageal squamous cell carcinoma (ESCC), which is the ninth highly aggressive malignancy. Tumor-infiltrating immune cells (TIIC) exert as major component of the tumor microenvironment (TME), showing possible prognostic value in ESCC.
Methods: Transcriptome data and scRNA-seq data of ESCC samples were extracted from the GEO and TCGA databases.
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