A comparative analysis was carried out between the hair content of basic trace metals in patients with atherosclerosis, ischemic heart disease (IHD) and findings from their immunogrammes. Close correlation was found out between changes in concentrations of Mn, Cu, Fe, Si, Zn, Ca and processes of activation of basic leucocyte populations characteristic of IHD course and alterations in humoral immune response peculiar to the above patients. Conclusions were reached about presence of the aforementioned changes in the pathogenesis of atherosclerosis, IHD.

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