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Screening for cardiac sarcoidosis: diagnostic approach and long-term follow-up in a tertiary centre.
Neth Heart J
January 2025
Department of Cardiology, Thorax Centre, Cardiovascular Institute, Erasmus Medical Centre, Rotterdam, The Netherlands.
Background: Cardiac sarcoidosis (CS) is associated with poor prognosis, making early diagnosis and treatment important. This study evaluated the results of a diagnostic approach in patients with known sarcoidosis and suspected cardiac involvement in a tertiary centre and their long-term outcomes.
Methods: We included 180 patients with sarcoidosis and a clinical suspicion of CS.
Transesophageal endosonography in the diagnosis of sarcoidosis: a narrative review.
Mediastinum
December 2024
Department of Respiratory Medicine, NHO Nagoya Medical Center, Nagoya, Japan.
Background And Objective: Transesophageal endosonography, including endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) and endoscopic ultrasound with bronchoscope-guided fine-needle aspiration (EUS-B-FNA), has been applied to the diagnosis of benign as well as malignant diseases. This narrative review summarizes the recent use of EUS-(B)-FNA in diagnosing sarcoidosis.
Methods: A comprehensive and systematic online literature search of PubMed was conducted using the keywords ("sarcoidosis"), and ("EUS" OR "EUS-FNA" OR "EUS-B" OR "EUS-B-FNA" OR "endoscopic ultrasound guided fine needle aspiration" OR "endoscopic ultrasound using the EBUS scope guided fine needle aspiration" OR "endoscopic ultrasound using the EBUS bronchoscope" OR "transesophageal" OR "transesophageal endoscopic ultrasound guided fine needle aspiration" OR "transesophageal bronchoscopic ultrasound guided fine needle aspiration").
Respiratory Pathology and Cardiovascular Diseases: A Scoping Review.
Open Respir Arch
November 2024
Translational Research In Airway Diseases Group (TRIAD), Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain.
Article Synopsis
- Respiratory diseases and cardiovascular diseases (CVDs) often share common risk factors, like aging and smoking, and their relationship can impact the prognosis of each condition.
- The interactions between these diseases involve shared mechanisms such as inflammation, oxidative stress, and microvascular dysfunction, which can exacerbate both respiratory and cardiovascular issues.
- Understanding the coexistence of these diseases is crucial for adjusting treatment plans and improving overall patient outcomes.
A case report: Endobronchial ultrasound guided biopsy of radiographically normal size thoracic lymph nodes supporting diagnosis of cardiac sarcoidosis.
Respir Med Case Rep
November 2024
Department of Pulmonary and Critical Care Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, OH, USA.
Article Synopsis
- Sarcoidosis is a rare chronic disease with an unclear cause, making cardiac sarcoidosis (CS) diagnosis particularly challenging.
- Current guidelines for diagnosing CS lack clinical validation, and while endomyocardial biopsy is specific, it is not very sensitive and has significant risks.
- A case study of a 63-year-old man diagnosed with CS through endobronchial ultrasound transbronchial needle aspiration (EBUS TBNA) of normal lymph nodes suggests that EBUS TBNA could be a viable option for diagnosing CS in cases without clear pulmonary sarcoidosis evidence.
More evidence that sarcoidosis is a host disease, and the identity of the aetiological triggers is irrelevant.
Eur Respir J
December 2024
Department of Pulmonary and Critical Care Medicine, Integrated Hospital Care Institute, Cleveland Clinic, Cleveland, OH, USA.
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