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Effects of Chemical Pretreatments of Wood Cellulose Nanofibrils on Protein Adsorption and Biological Outcomes.
ACS Appl Mater Interfaces
January 2025
Center of Translational Oral Research (TOR), Department of Clinical Dentistry, University of Bergen, Bergen 5009, Norway.
Wood-based nanocellulose is emerging as a promising nanomaterial in the field of tissue engineering due to its unique properties and versatile applications. Previously, we used TEMPO-mediated oxidation (TO) and carboxymethylation (CM) as chemical pretreatments prior to mechanical fibrillation of wood-based cellulose nanofibrils (CNFs) to produce scaffolds with different surface chemistries. The aim of the current study was to evaluate the effects of these chemical pretreatments on serum protein adsorption on 2D and 3D configurations of TO-CNF and CM-CNF and then to investigate their effects on cell adhesion, spreading, inflammatory mediator production , and the development of foreign body reaction (FBR) .
View Article and Find Full Text PDF"Minimal-Advice" on Salt Intake: Results of a Multicentre Pilot Randomised Controlled Trial on Hypertensive Patients.
High Blood Press Cardiovasc Prev
January 2025
Department of Clinical Medicine and Surgery, ESH Excellence Center of Hypertension, "Federico II" University of Naples Medical School, Via S. Pansini, 5, 80131, Naples, Italy.
Introduction: A strong and well-known association exists between salt consumption, potassium intake, and cardiovascular diseases. MINISAL-SIIA results showed high salt and low potassium consumption in Italian hypertensive patients. In addition, a recent Italian survey showed that the degree of knowledge and behaviour about salt was directly interrelated, suggesting a key role of the educational approach.
View Article and Find Full Text PDFUltrasound evaluation of gastric emptying for two different quantities of milk in elementary school-aged children.
Eur J Pediatr
January 2025
Department of Anesthesiology, Children's Hospital Affiliated to Shandong University & Jinan Children's Hospital, No. 23976, Jingshi Road, Jinan, 250012, China.
Unlabelled: Current guidelines recommend 6-h milk fasting in periprocedural settings; however, recent evidence suggests potential overconservativeness and supports more liberal pediatric fasting protocols. This study assessed the gastric emptying of two different milk quantities in elementary school-age children using gastric ultrasonography. This prospective crossover trial involved 30 healthy children who fasted overnight on two separate occasions within one month, consuming either 5 or 10 mL/kg of milk.
View Article and Find Full Text PDFHuman-biting behaviour of Leptoconops irritans (Diptera: Ceratopogonidae) in a touristic area of the Balearic Islands (Spain).
Parasitol Res
January 2025
Applied Zoology and Animal Conservation Group, University of the Balearic Islands (ZAP-UIB), Palma, Spain.
Biting midges of genus Leptoconops Skuse 1889 are small blood-feeding insects recognized as highly irritating diurnal pests in certain regions around the globe. In Europe, their presence is poorly documented, except in France and Italy. Following reports of human discomfort in a tourist area of Menorca, Balearic Islands (Spain), a small-scale study was conducted to identify the biting species and assess their preferred biting sites using a human-landing assay along a habitat gradient in a coastal dune area.
View Article and Find Full Text PDFDistribution analysis of RAB11A and RAB11B, small GTP-binding proteins, in mice.
Mol Biol Rep
January 2025
Department of Cellular Pathology, Institute for Developmental Research, Aichi Developmental Disability Center, 713-8 Kamiya, Kasugai, 486-0392, Japan.
Background: RAB11 is a small GTP-binding protein that regulates intracellular trafficking of recycling endosomes and is thereby involved in several neural functions. Highly similar RAB11 isoforms are encoded by RAB11A and RAB11B genes, and their pathogenic variants are associated with similar neurodevelopmental disorders, suggesting that RAB11A and RAB11B play similar and important roles in brain development. However, the detailed distribution patterns of these isoforms in various organs, including the brain, remain undetermined.
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