Breast reconstruction, i.e. enlargement of the breast by use of silicone implants, has been performed for almost 40 years. Due to its qualities silicone is being widely used in different branches of surgery. New scientific and technological knowledge have resulted in a variety of types of silicone implants (sheet, filling). There is a great interest, but also controversies concerning the development of breast cancer and connective tissue disease in implant bearing patients. There is no evidence on the influence of silicone implants on the breast cancer development. Regardless of the presence of the implant, standard mammography, additional tangential projections, Eklund's maneuver, ultrasonography in addition to a careful clinical examination are sufficient for an adequate follow-up and detection of even minimal changes within the breast tissue.
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Plast Reconstr Surg Glob Open
January 2025
From the Section General Internal Medicine, Department of Internal Medicine, Amsterdam Public Health Research Institute, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
Background: Explantation often alleviates symptoms in women with breast implant illness. However, persistent complaints in some cases may be linked to persistent silicone-induced inflammation from residual silicone particles. Positron emission tomography (PET) imaging could potentially detect this inflammation.
View Article and Find Full Text PDFEur J Ophthalmol
January 2025
Department of Ophthalmology, King's College Hospital, London, UK.
A 42 year old Afro-Caribbean man underwent Baerveldt Glaucoma Implant (BGI) surgery for silicone oil induced glaucoma. Three months following initial surgery, the 3-0 prolene ripcord suture was removed. Anterior segment OCT demonstrates the position of the intracameral portion of the tube before and after the 3/0 prolene stent suture (PSS) removal.
View Article and Find Full Text PDFMAGMA
January 2025
Translational Research Imaging Center (TRIC), Clinic of Radiology, University of Münster, Albert-Schweitzer-Campus 1, building A16, 48149, Münster, Germany.
Objective: Invasive multimodal fMRI in rodents is often compromised by susceptibility artifacts from adhesives used to secure cranial implants. We hypothesized that adhesive type, shape, and field strength significantly affect susceptibility artifacts, and systematically evaluated various adhesives.
Materials And Methods: Thirty-one adhesives were applied in constrained/unconstrained geometries and imaged with T2*-weighted EPI at 7.
Exp Eye Res
January 2025
Casey Eye Institute, Oregon Health & Science University, United States.
Animal models that help us understand how elevated intraocular pressure (IOP) causes axonal injury will lead to new glaucoma therapies. Because reliable measurements are difficult to obtain in chronic models, we developed the controlled elevation of IOP (CEI) approach. Here, a cannula connected to an elevated balanced salt solution (BSS) reservoir is inserted into the anterior chamber of anesthetized Brown Norway rats.
View Article and Find Full Text PDFInt Immunopharmacol
January 2025
Department of Plastic Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, PR China; National Key Clinical Specialty (Wound Healing), The First Affiliate d Hospital Of Wenzhou Medical University, PR China. Electronic address:
This study aimed to investigate the effects of silicone implants on the incidence of breast cancer in rats, as well as their impact on immune surveillance mechanisms. Female SD rats were divided into three groups: a Placebo Surgery Group (PSG), a Thoracic Implant Group (TIG), and a Back Implant Group (BIG). Following the corresponding surgical procedures, we measured Secretoglobin Family 2A, Member 2(SCGB2A2) and Mucin-1 (MUC1) antigen levels using ELISA, and statistical analyses were conducted to evaluate immune responses.
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