Serum immunoglobulins E are related to menstrual cycle.

Eur J Epidemiol

CNR Institute of Clinical Physiology and Second Division of Internal Medicine, University of Pisa, Italy.

Published: December 1997

During a cross sectional epidemiological survey on a general population sample, 596 fertile women underwent total serum IgE determination. They completed an interviewer-administered standardized questionnaire and were categorized according to their menstrual period. They were divided into two groups: those from days 10 to 20, who were considered to be in the periovulatory phase, and those in the other phases. IgE mean values were significantly different (p = 0.01) in the two groups: particularly, lower IgE values were found in those in periovulatory phase, after accounting for smoking habit and atopic status. By multiple regression analysis, taking into account the independent effects of menstrual period, age, smoking habit, hours of fast, skin prick test reactivity and presence of cough, significantly lower IgE values in the periovulatory phase were found. We hypothesize the possibility that a decrease of IgE concentration occurs during midcycle: a reduced immune response might facilitate the ovuli implantation. Further studies are necessary to longitudinally investigate the trend of IgE in the same women, as well as the distributions and the trends of other immunoglobulins.

Download full-text PDF

Source
http://dx.doi.org/10.1023/a:1007472407010DOI Listing

Publication Analysis

Top Keywords

periovulatory phase
12
ige values
12
menstrual period
8
lower ige
8
values periovulatory
8
smoking habit
8
ige
6
serum immunoglobulins
4
immunoglobulins menstrual
4
menstrual cycle
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!