Seven strains of Y. enterocolitica were screened for their enterotoxic activity. Three strains belonging to serogroups 0:3 and 0:9 elicited enterotoxic response in rabbit ligated gut segments and in infant mice. The enterotoxin resisted heat at 65 degrees and 100 degrees C for 20 min. The toxin was eluted in the second beak material during Sephadex G-75 gel filtration. On the basis of polyacrylamide disc gel electrophoresis the toxic component had a molecular weight of about 12,400.
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