The iodine concentration in the chain sow feed-->blood serum of dams-->milk-->blood serum of piglets (2 per litter) was determined in 36 litters in two experiments with different dietary iodine levels and in 16 litters in the framework of field studies in two piglet production farms in each case at weaning after four weeks lactation. In the blood serum also the concentration of thyroxine (T4) and triiodothyronine was determined. The serum concentration of iodine and T4 did not indicate dietary iodine administration (sows) or showed only a weak response (piglets). The iodine concentration of milk was very strongly affected by iodine administration and by the iodine status of sows prior to the experiments. The highest milk iodine concentration was found in the sows of piglet production farms, corresponding to the level of iodine administered. For diagnosis of the iodine supply status the iodine concentration of sow milk should be analyzed. The lower limit of milk iodine concentration is presently defined as 50 micrograms/l, and the mean of 5 random samples per sow herd should not fall below this limit. Serum concentrations of iodine and T4 may remain moderate even in case of a low iodine supply (sow serum: 30 micrograms iodine/l, 25 nmol T4/l; piglet's serum: 50 micrograms iodine/l, 55 nmol T4/l), and are unsuited for diagnosis of iodine status.
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Quant Imaging Med Surg
January 2025
Department of Radiation Oncology Physics & Technology, Cancer Hospital of Shandong First Medical University, Jinan, China.
Background: Breast cancer (BC) is a common cancer among women worldwide, and although the use of neoadjuvant therapy (NAT) for BC has become more widespread, there is no standardized prediction of the efficacy of NAT for BC. This study aimed to evaluate the value of quantitative parameters of dual-layer detector spectral computed tomography (DLCT) in predicting whether BC patients can achieve pathological complete response (pCR) after NAT.
Methods: Patients who were first diagnosed with BC in Shandong Cancer Hospital and Institute and received only NAT before surgery were selected for participation in this study.
J Arthroplasty
January 2025
Department of Orthopedic Surgery, Mayo Clinic, 200 First Street S.W., Rochester, MN, 55905.
Background: Native and periprosthetic joint infections are devastating conditions fraught with patient morbidity and mortality. Aseptic and septic joints are often debrided and irrigated to decrease bacterial loads when preventing or treating infection. However, the effect of clinically used irrigation solutions on the native cellular components of the synovial joint is unknown.
View Article and Find Full Text PDFNeurosurg Rev
January 2025
Neurosurgery Division, Department of Surgery, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria.
Ventriculoperitoneal (VP) shunting is frequently associated with complications of which shunt-related infections are the most common. However, controversies still exist regarding the underlying factors. This study comparing peri-operative skin preparation agents was aimed at determining which factors among previously documented determinants of shunt infection are implicated in our practice setting.
View Article and Find Full Text PDFObjectives: This study evaluates the performance of a clinical dual-source photon-counting computed tomography (PCCT) system in quantifying iodine within calcified vessels, using 3D- printed phantoms with vascular-like structures lined with calcium.
Methods: Parameters assessed include lumen diameters (4, 6, 8, 10, and 12 mm), phantom sizes (S: 20×20 cm, M: 25×25 cm, L: 30×40 cm, XL: 40×50 cm, representing the 99th percentile of US patient sizes), and iodine concentrations (2, 5, and 10 mg/mL). Scans were performed at radiation dose levels of 5, 10, 15, and 20 mGy to systematically evaluate iodine quantification accuracy and spectral imaging performance.
Clin Endocrinol (Oxf)
January 2025
Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, China.
Objectives: The relationship between iodine status and gestational diabetes mellitus (GDM) is inconclusive. This study aimed to explore the trajectories of urinary iodine concentrations (UIC) in pregnant women before GDM diagnosis and to assess the associations between maternal UIC trajectories and the risk of developing GDM.
Methods: A prospective cohort study was conducted in China.
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