A new noninvasive impedance method has been proposed to determine the permeability of skin capillaries, which involves measurement of the electric resistance of a skin area before and after exposure to negative pressure. There is a convergence of clinical data and simulation findings. The changes in the permeability coefficient were studied in different periods after recovery of adequate blood supply in the diseased limb. The investigation has allowed the developed permeability coefficient to be included into the algorithm of diagnosing and treating patients with arterial diseases.

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