[Cervical polyadenopathy due to Kikuchi and Fujimoto disease].

Rev Med Chil

Departamento de Endocrinología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago.

Published: March 1997

Kikuchi and Fujimoto disease is a benign subacute necrotizing lymphadenitis, probably associated to a viral infection, that affects mostly young Asian women. We report a 19 years old women, with a vast familiar history of thyroid disease (three uncles with papillary thyroid carcinoma and one with a Hashimoto thyroiditis). After an upper respiratory infection, she presented with painless cervical adenopathies. Cervical ultrasound examination detected an 8 mm thyroidal nodule. She was operated with the diagnosis of thyroidal cancer. The pathological examination confirmed that the nodule was a papillary thyroidal cancer, but the study of the resected lymph nodes, revealed a Kikuchi and Fujimoto disease.

Download full-text PDF

Source

Publication Analysis

Top Keywords

kikuchi fujimoto
12
fujimoto disease
8
thyroidal cancer
8
[cervical polyadenopathy
4
polyadenopathy kikuchi
4
fujimoto disease]
4
disease] kikuchi
4
disease benign
4
benign subacute
4
subacute necrotizing
4

Similar Publications

Article Synopsis
  • Autoinflammatory disorders are characterized by an exaggerated response of the innate immune system, primarily involving neutrophils and macrophages, and are differentiated from connective tissue diseases by the absence of anti-nuclear antibodies.
  • Many of these disorders are linked to inherited genetic mutations and tend to manifest in childhood or early adulthood, though some, like VEXAS syndrome, highlight the potential for acquired mutations in adults.
  • The review focuses on the cutaneous manifestations of various acquired autoinflammatory disorders, including adult-onset Still's disease and Schnitzler syndrome, which have significant diagnostic implications.
View Article and Find Full Text PDF

Kikuchi-Fujimoto disease (KFD) and adult-onset Still disease (AOSD) are two rare conditions whose association poses a significant diagnostic challenge. KFD is characterized by subacute necrotizing lymphadenitis of unknown etiology, primarily affecting young adults, and often presents with fever and posterior cervical lymphadenopathy. AOSD is a systemic inflammatory disorder of unclear origin, defined by high-spiking fever, lymphadenopathy, hepatosplenomegaly, hyperferritinemia, and leukocytosis.

View Article and Find Full Text PDF

Kikuchi-Fujimoto disease (KFD) is a rare self-limiting condition presenting as fever and cervical lymphadenopathy, with only two reported cases with isolated mediastinal lymphadenopathy. Lack of awareness about this condition often results in a high rate of misdiagnosis. We present a case of a 29-year-old Indian male with fever, mucocutaneous ulcers, weight loss, and mediastinal lymphadenopathy on CT.

View Article and Find Full Text PDF

Case Report of Asymptomatic Kikuchi-Fujimoto Disease.

Curr Med Imaging

November 2024

Department of Radiology, Weill Cornell Medicine, 425 East 61st Street, New York, NY, 10065, USA.

Background: Kikuchi-Fujimoto Disease (KFD) is a rare condition, distinguished by its hallmark presentation of regional lymphadenopathy in young adult females. While initially observed to exclusively affect cervical lymph nodes in females under 40 years old, KFD is now known to impact individuals of any age or gender and manifest with adenopathy in various anatomical sites. Nonspecific imaging findings for KFD include enlarged lymph nodes, often exhibiting abnormal morphology.

View Article and Find Full Text PDF

Kikuchi-Fujimoto Disease: A Case Series and Review of the Literature.

Diseases

November 2024

The Arkadi M. Rywlin M.D. Department of Pathology and Laboratory Medicine, Mount Sinai Medical Center, Miami Beach, FL 33140, USA.

Kikuchi-Fujimoto disease (KFD), also known as histiocytic necrotizing lymphadenitis, is a rare, self-limiting disorder characterized by fever typically lasting for 1 week up to 1 month and painful necrotizing lymphadenopathy, primarily affecting young adults of Asian ancestry. Although the exact cause remains unclear, infectious and autoimmune mechanisms have been implicated in the pathogenesis of the disease. In this case series, we aim to describe the histopathological features of KFD over a ten-year period at Mount Sinai Medical Center of Florida, and review the current understanding of its pathogenesis, clinical presentation, diagnosis, and management.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!