Long live the Queen's subjects.

Philos Trans R Soc Lond B Biol Sci

MRC Laboratory of Molecular Biology, Cambridge, UK.

Published: December 1997

In 1952, the Queen congratulated 255 people on their hundredth birthdays and 1135 couples on their sixtieth wedding anniversaries. By 1996, these numbers had risen to 5218 and 11,688, respectively. Semilogarithmic plots, normalized to constant numbers of births and marriages, show steady exponential rises in the number of centenarians with a doubling time of 11 years, and of diamond weddings with a doubling time of 19 years. An alternative plot of the numbers of those reaching a hundred between 1910 and 1990, based on registers of births and deaths and normalized to constant births, shows an annual rise of only 1% from 1910 to 1946, followed by a steady exponential rise with a doubling time of 12 years, closely matching that of 11 years derived from the Queen's figures. The exponential rise in the number of those born from 1846 onwards living to a hundred precedes by many years the general rise in the expectation of life at birth and the general drop in mortality from infectious diseases, but it coincides with the beginning of a steady rise in real wages. Another important factor may be improved medical treatment at old age from 1946 onwards.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1692135PMC
http://dx.doi.org/10.1098/rstb.1997.0178DOI Listing

Publication Analysis

Top Keywords

doubling time
12
time years
12
normalized constant
8
steady exponential
8
exponential rise
8
years
5
rise
5
long live
4
live queen's
4
queen's subjects
4

Similar Publications

Objectives: Anterior shoulder instability with minimal glenoid bone loss has several options for Bankart repair. We aimed to evaluate the results of a modified technique using two anchors with double and single loaded suture (three stitches in total) in arthroscopic Bankart surgery.

Methods: Thirty-eight patients underwent arthroscopic Bankart surgery and were assessed after an average 40 months follow-up.

View Article and Find Full Text PDF

Introduction: Functional beverages are increasingly popular but it is important to validate their purported effects through research. The aim of the current study was to investigate the effects of a new functional energy shot on cognitive performance and mood states in healthy adults, with a focus on measuring mental energy enhancement and attenuation of negative effects associated with extended performance of mentally demanding tasks.

Methods: This study was a randomized, double-blind, placebo-controlled, crossover trial.

View Article and Find Full Text PDF

Objectives: Private healthcare is a rapidly growing industry in the UK, particularly for surgical procedures, due to extensive waiting times in publicly funded health care. The NHS also commissions private healthcare to provide procedures for NHS patients to alleviate waiting times. We aimed to explore the trends and geographical variations between the North and South of England in privately funded and NHS-funded privately delivered orthopaedic procedures compared to NHS waiting times.

View Article and Find Full Text PDF

Objectives: International guidelines recommend integrase strand-transfer inhibitor (INSTI)-based regimens as initial and switch therapy in people with HIV. As novel INSTIs become available, understanding how emergence of resistance at virological failures and seroconversions affects subsequent treatment options is needed. For the latest approved INSTI, cabotegravir, resistance patterns comprising Q148K/R, N155H, R263K, G118R, E138A/K and G140A/S (alone or in combination) have been documented in virological failures and seroconversions.

View Article and Find Full Text PDF

Background: The effect of oral Cannabidiol (CBD) on interference during learning and memory (L&M) in healthy human volunteers has not been studied.

Method: A two-arm crossover, randomized, double-blind, placebo-controlled trial was conducted at Colorado State University Pueblo (CSU Pueblo) to evaluate the effects of 246 mg oral CBD on L&M in healthy adults. Among 57 healthy volunteers enrolled, 35 were included in the analyses.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!