Objective: This study was undertaken to evaluate the effectiveness and the results with the Konno-aortoventriculoplasty.
Methods: Over a 10-year period, 21 Konno-aortoventriculoplasties were performed in 20 patients utilizing mechanical cardiac valvular prostheses, in 14 male and 6 female patients for complex left ventricular outflow tract stenosis. The mean age was 9.2 years (range 1.7-25.7 years). The pre-enlargement mean aortic annular size was 11.5 mm (6-16 mm). The mean size of the prostheses implanted was 20.4 mm (19-23 mm). In a typical case, the aortic annulus was enlarged to twice its original size.
Results: The only operative death was in a 8 kg, 20-month old child with previous commissurotomy, due to intractable bleeding and low output state. The mean hospital stay was 9.4 days (1-15 days), and the mean ICU stay was 3.3 days (1-7 days). The only late death was in a patient who went on to have cardiac transplantation for progressive left ventricular dysfunction. The 10-year acturial survival was 90 +/- 7%, and the reoperation free survival was 89 +/- 7%. All of the 18 surviving patients are asymptomatic at the time of last clinic visit (mean follow-up of 61.1 +/- 31.7 months, range 0-139 months). All patients had resolutions of their left ventricular hypertrophy with insignificant gradient across the repair by echocardiography.
Conclusions: Konno-aortoventriculoplasty is extremely effective in the treatment of small aortic annuli and complex left ventricular outflow tract obstruction. In the present era of increasing popularity of autograft and homograft operations, the Konno procedure should remain in the technical armamentarium of the cardiac surgeon.
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http://dx.doi.org/10.1016/s1010-7940(97)00221-2 | DOI Listing |
Background: Reduced insulin secretion is linked to diabetes and cardiovascular disease (CVD), but its role in non-diabetic CVD patients is unclear. The homeostasis model assessment of β-cell function (HOMA-β) measures pancreatic β-cell function. This study investigated the association between HOMA-β and adverse cardiovascular events in non-diabetic CVD patients.
View Article and Find Full Text PDFBMJ Case Rep
January 2025
Cardiovascular and Thoracic Surgery, University of Louisville School of Medicine, Louisville, Kentucky, USA.
Our patient presented to the emergency room following a motor vehicle accident. The traumatic tricuspid valve rupture was diagnosed by transthoracic echocardiogram, and his respiratory status declined rapidly. He was placed on veno-venous extracorporeal membrane oxygenation (VV ECMO) to bridge him to surgical repair.
View Article and Find Full Text PDFHeart
January 2025
Division of Cardiovascular Research, School of Medicine, University of Dundee, Dundee, UK
Background: Early heart failure (HF) diagnosis is crucial to ensure that optimal guideline-directed medical therapy (GDMT) is administered to reduce morbidity and mortality. Limited access to echocardiography could lead to a later diagnosis for patients, for example, during an HF hospitalisation (hHF). This study aimed to compare the incidence and outcomes of inpatient versus outpatient diagnosis of HF.
View Article and Find Full Text PDFEur J Endocrinol
January 2025
Department of Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands.
Objective: Cardiovascular disease in acromegaly patients remains a major cause of morbidity and all-cause mortality. This systematic review investigates the effect of the first growth hormone lowering intervention on cardiac parameters.
Design: Systematic review.
Ann Endocrinol (Paris)
January 2025
Gazi University, Faculty of Medicine, Department of Endocrinology and Metabolism, Ankara, Turkey. Electronic address:
Aim: Co-existing primary aldosteronism (PA) and autonomous cortisol secretion (ACS) has been recently recognized as a distinct entity. This study aimed to assess the incidence of ACS in patients with PA, and its impact on clinical and laboratory parameters.
Methods: Ninety-two patients diagnosed with PA were included.
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