In spite of a part of unavoidable subjectivity, it seems that the use of antidepressive, anxiolytic and hypnotic agents has increased over the past years, but with a certain recent stabilization in the consumption of benzodiazepines. A slipping towards the medicalization of problems yet principally social is generally admitted. The following factors are specially considered: the type of request of the person, often dominated by a behaviour of "relieved" people; the medical answers, frequently marked with a preferential if not exclusive rest on the chemical molecule; the financial limitations imposed by the national level, very probable indirect origin of changes in the medical status and role, therefore of distortions concerning the therapeutic relation; a contrario, marketing phenomena involved in large economic challenges. In front of that conflict situation, we must hope for a keeping of the liberty of exercise of the physician, for the benefit of the patient.
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BMJ Oncol
April 2024
National Cancer Institute, Center for Global health, Rockville, Maryland, USA.
Introduction: Research is an essential pillar of cancer control and key in shaping regional cancer control agendas. Imbalances in science and technology in terms of lack of female participation have been well documented. However, there is little evidence about country-level female participation in cancer research.
View Article and Find Full Text PDFFront Artif Intell
January 2025
Independent Researcher, Hamburg, Germany.
Introduction: Artificial Intelligence (AI) is a transformative technology impacting various sectors of society and the economy. Understanding the factors influencing AI adoption is critical for both research and practice. This study focuses on two key objectives: (1) validating an extended version of the Technology Acceptance Model (TAM) in the context of AI by integrating the Big Five personality traits and AI mindset, and (2) conducting an exploratory k-prototype analysis to classify AI adopters based on demographics, AI-related attitudes, and usage patterns.
View Article and Find Full Text PDFIntensive Care Med Exp
January 2025
Department of Cardiac Surgery, Lanzhou University Second Hospital, Lanzhou University, No. 80, Cuiyingmen, Chengguan District, Lanzhou, 730030, China.
Background: Although extracorporeal membrane oxygenation (ECMO) is an effective technique for life support, the incidence of acute kidney injury (AKI) during ECMO support remains high. Dexmedetomidine (DEX), which has been widely used for sedation during ECMO, possesses several properties that help reduce the occurrence of AKI. This study aimed to investigate the protective effect of DEX on kidney function during ECMO.
View Article and Find Full Text PDFExpert Rev Neurother
January 2025
Headache Centre, Department of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy.
Introduction: When a first anti-CGRP monoclonal antibody (anti-CGRP mAb) fails, switching to a different anti-CGRP mAb is an option often considered, despite this approach is not yet systemically studied.
Methods: We present the findings of a systematic review conducted according to the PRISMA recommendations on published studies - of any design - investigating the clinical outcomes after switching for any reason to different anti-CGRP mAbs.
Results: The literature search retrieved 76 records, while 19 papers were eventually reviewed.
Nefrologia (Engl Ed)
January 2025
Division of Nephrology IIS-Fundacion Jimenez Diaz, Department of Medicine, Universidad Autónoma de Madrid, Madrid, Spain; RICORS2040, Carlos III Institute of Health, Madrid, Spain.
Introduction: Chronic kidney disease (CKD) is associated with high cardiovascular disease (CVD) risk, and requires specific interventions to decreases CVD risk. The guidelines indicate that systematic global CVD risk assessment is recommended in individuals with any major vascular risk factor. The European Society Cardiology (ESC) guidelines, he European Renal Association (ERA) Council and the Spanish Society of Nephrology (S.
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