Plasmodium falciparum antigens SERP, HRPII, MSAI, and 41-3 have shown promise as vaccine components. This study aimed at reproducing and extending previous results using three hybrid molecules. Antibody responses were reproduced in Aotus monkeys, but solid protection from a P. falciparum blood-stage challenge that showed an unintendedly enhanced pathogenicity was not observed.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC107908 | PMC |
| http://dx.doi.org/10.1128/IAI.66.1.373-375.1998 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Three novel neoplasms in Nancy Ma's owl monkeys ().
Vet Pathol
December 2024
The University of Texas MD Anderson Cancer Center, Bastrop, TX.
Neoplasms are only sporadically reported in New World primates and rarely in owl monkeys (), specifically. Previous reports of neoplasms in owl monkeys are primarily restricted to lymphoma induced by infection, although other tumors in the central nervous, genitourinary, gastrointestinal, and endocrine systems have been sporadically reported. Herein, we describe 3 previously unreported neoplasms in owl monkeys () including a pericardial mesothelioma in a 6-year-old male, a nephroblastoma in a 2-year-old male, and a cervical neoplasm with characteristics of an epithelioid trophoblastic tumor in a 4-year-old female, all occurring in the same closed breeding colony at a research facility in central Texas.
View Article and Find Full Text PDFReports of Corneal Opacity in Wild Andean Night Monkeys (Aotus lemurinus) in the Colombian Andes.
J Med Primatol
December 2024
Laboratorio de Ecología de Bosques Tropicales y Primatología (LEBTYP), Universidad de los Andes, Bogotá, Colombia.
Morphological abnormalities are rarely reported in night monkeys; in particular, eye problems in wild individuals are relatively rare in the literature. We present for the first time a record of corneal opacity in two wild individuals of the species Aotus lemurinus in the Andean region of Colombia. In this study, we found cases of corneal opacity probably associated with infectious and contagious processes, injuries resulting from attacks, the age of the individuals, and the health status of the groups in wildlife.
View Article and Find Full Text PDFInbreeding avoidance, competition and natal dispersal in a pair-living, genetically monogamous mammal, Azara's owl monkey ().
R Soc Open Sci
August 2024
Owl Monkey Project, Fundación ECO, Formosa, Argentina.
Natal dispersal is an important life-history stage influencing individual fitness, social dynamics of groups and population structure. Understanding factors influencing dispersal is essential for evaluating explanations for the evolution and maintenance of social organization, including parental care and mating systems. The social and mating systems of Azara's owl monkeys () are infrequent among mammals; these primates are pair-living, serially and genetically monogamous and both sexes directly care for offspring.
View Article and Find Full Text PDFThe social and defensive function of olfactory behaviors in a pair-living sexually monogamous primate.
Am J Primatol
September 2024
The Owl Monkey Project, Fundación ECO, Formosa, Argentina.
Olfactory behaviors serve a wide variety of social functions in mammals. Odor may signal information about attributes of individuals important for mating and reproduction. Olfactory behaviors, such as scent-marking, may also function as part of home range or resource defense strategies.
View Article and Find Full Text PDFReactivity of HLADR antibody manifests expression of surface MHC II molecules on peripheral blood T lymphocytes in new world monkeys.
Immun Inflamm Dis
June 2024
Department of Comparative Medicine, Keeling Center for Comparative Medicine and Research, UT-MD Anderson Cancer Center, Bastrop, Texas, USA.
Background: Major histocompatibility complex (MHC) class II molecules expressed on B cells, monocytes and dendritic cells present processed peptides to CD4 T cells as one of the mechanisms to combat infection and inflammation.
Aim: To study MHC II expression in a variety of nonhuman primate species, including New World (NWM) squirrel monkeys (Saimiri boliviensis boliviensis), owl monkeys (Aotus nancymae), common marmosets (Callithrix spp.), and Old World (OWM) rhesus (Macaca mulatta), baboons (Papio anubis).
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!