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Effect of a prescription digital therapeutic for chronic insomnia on post-treatment insomnia severity, depression, and anxiety symptoms: results from the real-world DREAM study.
Front Psychiatry
September 2024
Nox Health, Alpharetta, GA, United States.
Introduction: Chronic insomnia is a substantial public health burden that often presents with co-occurring depression and anxiety. Randomized clinical trials and preliminary real-world evidence have shown that digitally delivered cognitive-behavioral therapy for insomnia (dCBT-I) is associated with improvements in insomnia, but real-world evidence is needed to determine the true impact of digital CBT-I. This pragmatic study aimed to evaluate the benefits of treating chronic insomnia with a tailored prescription digital therapeutic in a real-world population.
View Article and Find Full Text PDFSurfaced Mn-Mn Dimeric Sites Dictate CO Hydrogenation Activity and C Selectivity over MnRh Binary Catalysts.
J Am Chem Soc
October 2024
Collaborative Innovation Center of Chemistry for Energy Material, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Key Laboratory of Computational Physical Science, Department of Chemistry, Fudan University, Shanghai 200433, China.
Massive ethanol production has long been a dream of human society. Despite extensive research in past decades, only a few systems have the potential of industrialization: specifically, Mn-promoted Rh (MnRh) binary heterogeneous catalysts were shown to achieve up to 60% C oxygenates selectivity in converting syngas (CO/H) to ethanol. However, the active site of the binary system has remained poorly characterized.
View Article and Find Full Text PDFHow to Use Continuous Glucose Monitoring Efficiently in Diabetes Management: Opinions and Recommendations by German Experts on the Status and Open Questions.
J Diabetes Sci Technol
August 2024
Science Consulting in Diabetes GmbH, Düsseldorf, Germany.
Today, continuous glucose monitoring (CGM) is a standard diagnostic option for patients with diabetes, at least for those with type 1 diabetes and those with type 2 diabetes on insulin therapy, according to international guidelines. The switch from spot capillary blood glucose measurement to CGM was driven by the extensive and immediate support and facilitation of diabetes management CGM offers. In patients not using insulin, the benefits of CGM are not so well studied/obvious.
View Article and Find Full Text PDF"As long as you have a dream and as long as you work hard, your dream will come true".
J Orthop Sci
September 2024
Department of Orthopaedic Surgery, School of Medicine, Kawasaki, Kanagawa, Japan. Electronic address:
Background: Some young physicians decide their ultimate life goals early in life. The purpose of this article is to convey the message with feeling that because everyone lives only once, I want them to try many various things.
Method: The author introduces several unpredictable episodes that became watershed moments for him, and describes how he each behaved.
CVOT Summit Report 2023: new cardiovascular, kidney, and metabolic outcomes.
Cardiovasc Diabetol
March 2024
Forschergruppe Diabetes e. V, Helmholtz Center Munich, Ingolstaedter Landstraße 1, 85764, Neuherberg (Munich), Germany.
Article Synopsis
- The 9th Cardiovascular Outcome Trial (CVOT) Summit took place online from November 30 to December 1, 2023, focusing on recent outcomes trials involving medications like dapagliflozin, semaglutide, and bempedoic acid aimed at reducing major cardiovascular events and improving metabolic health.
- A diverse group of healthcare professionals discussed updates in the management of cardiovascular disease in patients with diabetes, heart failure, and chronic kidney disease, alongside the latest treatments for type 1 diabetes and obesity.
- The Summit emphasized the need for diversity in clinical trial participants and the importance of patient-reported outcomes, advocating for personalized treatment strategies and the integration of continuous glucose monitoring technology in managing diabetes
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