Animals were kept for 24 hours at 3-5 degrees C in sea water to which 100 mg% of glucose was added. Control animals were kept in the sea water without glucose. In gut epithelium of the lancelot 3 types of cells were revealed which correspond to those described earlier, viz. "digestive", "zymogen" and fine granular ones. Cytoplasm of the cells of the III type contains numerous granules of paraldehydefuchsine-positive material. After glucose loading, degranulation of the cytoplasm in these cells is more intensive than in cells of two other types. The product is released into the gut. The possibility of production of insulin or insulin-like substance by the cells of the III type is discussed.
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