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Orally-Administrable Supramolecular Probiotic Capsules Enable Cooperative Colon-Targeted Inflammation Inhibition for Ameliorating Ulcerative Colitis.
Acta Biomater
January 2025
School of Life Sciences, Chongqing University, Chongqing, 400044, China.. Electronic address:
Ulcerative colitis (UC) is a prevalent gastrointestinal disease characterized by the chronical and refractory inflammation of colorectal mucosa and walls, which severely impairs overall well-being of individuals. Probiotics has shown tremendous promise for UC therapy due to its multifaceted mucosal barrier restoration and immunomodulation capabilities. Nevertheless, the successful administration of probiotics remains a clinical obstacle.
View Article and Find Full Text PDFEffects of Electroacupuncture Per-Conditioning at Huantiao on Motor Function Recovery in Acute Cerebral Ischemia Mice.
Physiol Behav
January 2025
Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China; Department of Rehabilitation Medicine, Huashan Hospital, Fudan University, Shanghai, 200040, China. Electronic address:
Background: Continuous electroacupuncture pre-conditioning (EPRC) and post-conditioning (EPOC) effectively improve motor dysfunction after acute cerebral ischemia, but they require multiple treatments. Recently, electroacupuncture per-conditioning (EPEC) has demonstrated neuroprotective effects, indicating that this single-session intervention has short-term efficacy.
Objective: To evaluate the effect of EPEC at Huantiao (GB30) on motor recovery in acute cerebral ischemia mice.
Effects of treadmill running on anxiety- and craniofacial pain-like behaviors with histone H3 acetylation in the brain of mice subjected to social defeat stress.
PLoS One
January 2025
Division of Oral Physiology, Faculty of Dentistry, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
This study examined the effects of treadmill running (TR) regimens on craniofacial pain- and anxiety-like behaviors, as well as their effects on neural changes in specific brain regions of male mice subjected to repeated social defeat stress (SDS) for 10 days. Behavioral and immunohistochemical experiments were conducted to evaluate the impact of TR regimens on SDS-related those behaviors, as well as epigenetic and neural activity markers in the anterior cingulate cortex (ACC), insular cortex (IC), rostral ventromedial medulla (RVM), and cervical spinal dorsal horn (C2). Behavioral responses were quantified using multiple tests, while immunohistochemistry measured histone H3 acetylation, histone deacetylases (HDAC1, HDAC2), and neural activity markers (FosB and phosphorylated cAMP response element-binding protein (pCREB).
View Article and Find Full Text PDFEarly Mobilization in Post-Orthopedic Surgery Patients: A Scoping Review.
J Multidiscip Healthc
January 2025
Department of Fundamental Nursing, Faculty of Nursing, Padjadjaran University, Sumedang, West Java, Indonesia.
Post-orthopedic surgery patients need to undergo a recovery process with immobilization to minimize pain or swelling. Maximum care through early mobilization intervention can accelerate the return of body function and minimize medical complications. This literature review aims to determine early mobilization-based interventions that can be applied to post-orthopedic surgery patients.
View Article and Find Full Text PDFDiversity and composition of vegetation and soil seed banks after sand dune restoration by oil mulching and plantations.
Sci Rep
January 2025
Department of Range and Watershed Management, Faculty of Agriculture, Ilam University, Ilam, Iran.
Soil seed bank (SSB) is valuable reserves of seeds hidden in the soil and are especially important for the preservation and establishment of vegetation under adverse environmental conditions. However, there is a lack of knowledge on the effects of restoration measures on SSB, especially in arid ecosystems. Here, we assess the impacts of oil mulching (1 and 3 years after mulching) and plantations (15-year-old) on the diversity and composition of SSB and aboveground vegetation (AGV) in comparison with those in non-restored areas (i.
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