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Long-term follow-up of living liver donors: A single-center experience.
Liver Transpl
September 2022
Living donors are healthy individuals who are exposed to a major surgical procedure during which a major part of their liver is resected. Data on the long-term consequences of living liver donation are scarce. This study examined clinical, laboratory, and long-term health-related quality of life (HRQoL) in 237 living liver donors and 239 matched controls during 48-168 months of postdonation follow-up.
View Article and Find Full Text PDFOutcomes of kidney donors with sickle cell trait: A preliminary analysis.
Clin Transplant
June 2022
Department of Medicine, Houston Methodist Hospital, Houston, Texas, USA.
Most transplant centers do not screen kidney donor candidates for sickle cell trait (SCT) and many decline candidates with SCT since it may associate with kidney disease. We compared 17 kidney donors with SCT to propensity score matched donor controls on mortality, reduced eGFR, proteinuria and kidney failure. The prevalence of SCT in African American (AA) donors was 11 per 1000 compared to 73 per 1000 in non-donor AA.
View Article and Find Full Text PDFIntermediate Renal Outcomes, Kidney Failure, and Mortality in Obese Kidney Donors.
J Am Soc Nephrol
November 2021
Department of Pathology and Genomic Medicine, Institute for Academic Medicine, Houston Methodist Research Institute, Houston, Texas.
Background: Obesity is associated with the two archetypal kidney disease risk factors: hypertension and diabetes. Concerns that the effects of diabetes and hypertension in obese kidney donors might be magnified in their remaining kidney have led to the exclusion of many obese candidates from kidney donation.
Methods: We compared mortality, diabetes, hypertension, proteinuria, reduced eGFR and its trajectory, and the development of kidney failure in 8583 kidney donors, according to body mass index (BMI).
A mixed DNA profile controversy revisited.
J Forensic Sci
January 2022
Department of Statistics, University of Auckland, Auckland, New Zealand.
Semaan et al. (J Forensic Res, 2020, 11, 453) discuss a mock case "where eight different individuals [P through P ] could not be excluded in a mixed DNA analysis. Even though … expert DNA mixture analysis software was used.
View Article and Find Full Text PDFObstetric outcomes in pregnancies resulting from in vitro fertilization are not different in fertile, sterilized women compared to infertile women: A Society for Assisted Reproductive Technology database analysis.
Fertil Steril
March 2021
Center for Assisted Reproduction, Bedford, Texas. Electronic address:
Objective: To compare obstetric and neonatal outcomes resulting from assisted reproductive technology in couples with a history of female sterilization to couples with other infertility diagnoses.
Design: Retrospective cohort study.
Setting: Not applicable.
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