At the neolithic period, collective burial-sites were common. In these deposits, we can observe a breakdown of bodies according to age and sex. The nature of this selection is completely unknown. It is a cultural or a family-based selection? We decided to approach this problem by doing a genetic study of the skeletons of the collective deposit of Condé-sur-Ifs (7,000 years B.P., Calvados, France). The study based on the variability of the mitochondrial DNA control region shows that the five individuals studied have all different mitochondrial types. Thus, a familial relationship between these individuals (on a maternal lineage) can be excluded.
Download full-text PDF |
Source |
---|
Epidemiol Prev
March 2025
Istituto di Fisiologia Clinica, Consiglio Nazionale delle Ricerche, Pisa.
Objectives: to analyse the prevalence and characteristics of the hikikomori phenomenon in Italy within a representative sample of students aged 15 to 19 years, assessing the factors associated with this behaviour to guide preventive interventions.
Design: cross-sectional study based on anonymous data collected through the ESPAD®Italia (European School Survey Project on Alcohol and other Drugs) survey using a self-administered questionnaire.
Setting And Participants: a representative sample of Italian high-school students is selected annually to ensure the comparability of ESPAD®Italia estimates.
Front Immunol
March 2025
College of Medicine, Yanbian University, Yanji, China.
Introduction: Alzheimer's disease (AD), a prevalent neurodegenerative disease, is primarily characterized by progressive neuron loss and memory impairment. NOD-like receptors (NLRs) are crucial for immune regulation and maintaining cellular homeostasis. Recently, NLRs have been identified as important contributors to neuroinflammation, thus presenting a potential approach for reducing inflammation and slowing AD progression.
View Article and Find Full Text PDFFront Fungal Biol
February 2025
Laboratório de Avaliação e Promoção da Saúde Ambiental, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
The emerging fungal pathogen () has been increasingly detected in environmental and animal samples, although studies in this regard are still scarce, especially in fisheries contexts. This study reports the first-time detection of in a commercially relevant fish species belonging to the Sciaenidae family ( sp.), indicating its potential emergence as a pathogen in Brazil.
View Article and Find Full Text PDFFront Cardiovasc Med
February 2025
Aortic Institute at Yale-New Haven, Yale University School of Medicine, New Haven, CT, United States.
Thoracic aortic aneurysm and dissection (TAAD) significantly impact cardiovascular morbidity and mortality. A large subset of TAAD cases, particularly those with an earlier onset, is linked to heritable genetic defects. Despite progress in characterizing genes associated with both syndromic and non-syndromic heritable TAAD, the causative gene remains unknown in most cases.
View Article and Find Full Text PDFFront Pharmacol
February 2025
Department of Experimental Research, Sun Yat-sen University Cancer Center, Guangzhou, China.
Introduction: Multi-drug resistance (MDR) is one of the leading reasons that cause the failures of cancer treatment. Novel agents that may reverse MDR and neutralize drug-resistant cancer cells are highly desirable for clinical practice. The targeting of cellular redox homeostasis and/or mitochondria-mediated energy metabolism are promising strategies for the suppression of drug-resistant cancer cells.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!