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Mental health and socio-cognitive predictors of adherence to COVID-19 social distancing rules in adolescents in England.
Heliyon
January 2025
Institute of Cognitive Neuroscience, University College London, UK.
The COVID-19 pandemic prompted governments worldwide to introduce social distancing measures, including school closures and restrictions on in-person socialising. However, adherence to social distancing was challenging for many - particularly adolescents, for whom social interaction is crucial for development. The current study aimed to identify individual-level influences on adherence to social distancing in a longitudinal sample of adolescents aged 11-20 years in England, who took part in a randomised controlled trial.
View Article and Find Full Text PDFLatino Sexual Minority Men's Pre-Exposure Prophylaxis Modality Preferences: A Latent Class Analysis.
AIDS Patient Care STDS
January 2025
School of Nursing and Health Studies, University of Miami, Coral Gables, Florida, USA.
Pre-exposure prophylaxis (PrEP) is an effective HIV prevention tool available in several modalities (e.g., daily oral, injectable, implants, rectal douching).
View Article and Find Full Text PDFIntegrative multiomics reveals common endotypes across PSEN1, PSEN2, and APP mutations in familial Alzheimer's disease.
Alzheimers Res Ther
January 2025
Department of Bioengineering, University of California, San Diego, La Jolla, CA, 92093, USA.
Background: PSEN1, PSEN2, and APP mutations cause Alzheimer's disease (AD) with an early age at onset (AAO) and progressive cognitive decline. PSEN1 mutations are more common and generally have an earlier AAO; however, certain PSEN1 mutations cause a later AAO, similar to those observed in PSEN2 and APP.
Methods: We examined whether common disease endotypes exist across these mutations with a later AAO (~ 55 years) using hiPSC-derived neurons from familial Alzheimer's disease (FAD) patients harboring mutations in PSEN1, PSEN2, and APP and mechanistically characterized by integrating RNA-seq and ATAC-seq.
Role of violence exposure on altruistic behavior and grit among emergency nurses in rural hospitals.
Int Nurs Rev
March 2025
College of Nursing, Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Aim: To explore the effect of violence exposure on altruistic behavior and grit among emergency nurses in 103-bed emergency departments in rural hospitals in Egypt.
Background: Workplace violence is a pervasive issue in emergency departments. Nurses in rural hospitals, facing limited resources and isolation, may be even more vulnerable to the adverse effects of workplace violence.
What Makes Non-Directed Living Kidney Donors Tick? Actionable Items to Increase Non-Directed Live Organ Donation.
Clin Transplant
December 2024
Department of Surgery, Columbia University Irving Medical Center, New York, New York, USA.
Article Synopsis
- Non-directed organ donation in the U.S. has seen a massive 90-fold increase from 1999 to 2019, but there’s limited research on why people choose to donate without a specific recipient in mind.
- A survey at CUIMC from 2009 to 2021 revealed that most kidney NDDs were motivated by previous altruistic actions, with a significant portion influenced by their religious beliefs and personal connections to organ donation stories.
- The study concluded with six recommended actions to enhance non-directed donations, including targeted outreach to altruistic individuals, promoting transplant stories, and addressing financial barriers related to donation.
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