A 56-year-old man with peripheral T1N0M0 lung cancer underwent thoracotomy. Pleural dissemination was recognized intraoperatively. We performed wedge resection of the lung including the primary tumor, and applied hypotonic cisplatin treatment. We followed this up postoperatively with chemotherapy combined with cisplatin and irinotecan. One year later, a recurrent tumor occurred at the resected end of the lung, so we conducted stereotactic radiosurgery on the recurrent lung lesion, resulting in complete eradication. One year later, no relapse of cancer was observed. We conclude that implementing hypotonic cisplatin treatment in pleural dissemination of lung cancer followed by stereotactic radiosurgery on any recurrent tumor in the peripheral lung was effective for the present case.
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