The Event Related Potential (ERP) of 8 french right handed subjects were recorded with 5 active electrodes located in frontal (Fz), central (Cz), occipital (Oz) and right/left parietal (RH, LH) sites while they were performing a modified version of the test of Stroop. They had either to read the names of basic colors (yellow, green, blue, red) written in the same colors (red written in red: concordant stimuli) or in a different color (red written in blue: discordant stimuli) or to name mentally the color in which was written the name of a color, both colors being concordant or discordant. The ERPs for reading were similar for concordant and discordant stimuli and showed no sign of a N400 wave, this was also the case for the mental naming of a color associated to the written name of the same color. A N400 wave with a Cz location was evident for the mental naming of a color when it was associated to the written name of another color. In this last case, the automatic reading of the name of a color would correspond to a priming which interferes with the access to the target word: the name of another color that the subject is required to evoke mentally.
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http://dx.doi.org/10.3109/00207459708986367 | DOI Listing |
Genome Med
January 2025
Otology & Neurotology Group CTS495, Instituto de Investigación Biosanitario, Ibs.GRANADA, Universidad de Granada, 18071, Granada, Spain.
Background: Familial Meniere's disease (FMD) is a rare polygenic disorder of the inner ear. Mutations in the connexin gene family, which encodes gap junction proteins, can also cause hearing loss, but their role in FMD is largely unknown.
Methods: We retrieved exome sequencing data from 94 individuals in 70 Meniere's disease (MD) families.
Eruptive pseudoangiomatosis (EP) is a rare cutaneous condition that usually resolves spontaneously within a few days and is more frequently seen in the pediatric age group. It is characterized by the sudden onset of asymptomatic small erythematous hemangioma-like papules encircled by a pale halo. The precise pathogenesis is unknown; however, multiple environmental triggers have been reported.
View Article and Find Full Text PDFWorld Psychiatry
February 2025
Department of Psychiatry, University of Campania "L. Vanvitelli", Naples, Italy.
This is the first bottom-up review of the lived experience of postpartum depression and psychosis in women. The study has been co-designed, co-conducted and co-written by experts by experience and academics, drawing on first-person accounts within and outside the medical field. The material initially identified was shared with all participants in a cloud-based system, discussed across the research team, and enriched by phenomenological insights.
View Article and Find Full Text PDFGenome Med
January 2025
Hereditary Cancer Group, Oncobell Program, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), Av. Gran Via 199-203, L'Hospitalet del Llobregat, 08908, Spain.
Background: Germline heterozygous pathogenic variants (PVs) in TP53 cause Li-Fraumeni syndrome (LFS), a condition associated with increased risk of multiple tumor types. As the associated cancer risks were refined over time, clinical criteria also evolved to optimize diagnostic yield. The implementation of multi-gene panel germline testing in different clinical settings has led to the identification of TP53 PV carriers outside the classic LFS-associated cancer phenotypes, leading to a broader cancer phenotypic redefinition and to the renaming of the condition as "heritable TP53-related cancer syndrome" (hTP53rc).
View Article and Find Full Text PDFBMJ Open
December 2024
Research and Development Center for New Medical Frontiers, Department of Advanced Medicine, Division of Neonatal Intensive Care Medicine, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Objectives: Inhaled nitric oxide (iNO) is a known treatment for pulmonary hypertension (PH) associated with bronchopulmonary dysplasia in preterm infants after 7 days of age (postacute phase). However, a consensus regarding the optimal criteria for initiating iNO therapy in this population in the postacute phase is currently lacking. This study, therefore, aimed to identify the criteria for initiating iNO therapy, alongside the associated clinical and echocardiographic findings, in this population.
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