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Influence of plasma exosomes from women living with HIV Stratified by HAND on monocyte subpopulations from healthy women without HIV.
J Neurovirol
January 2025
Department of Pharmacology and Toxicology, Medical Sciences Campus, University of Puerto Rico, San Juan, 00936-5067, Puerto Rico.
The role of plasma exosomes from people living with HIV (PLWH) with HAND in the phenotypic profile of uninfected monocytes remains unknown. We hypothesized that these exosomes influence the CD14/CD16 phenotypical profile of uninfected monocytes in a time-dependent manner. Exosomes were collected via ultracentrifugation from the plasma of women living with HIV (WLWH) and healthy controls stratified according to their cognition into normal cognition (NC) or symptomatic neurocognitive impairment (SNI) groups.
View Article and Find Full Text PDFSexually Explicit Media Exposure, Sexual Violence Victimization, and Sexual Risk Behaviors Among HIV-Positive Men Who Have Sex with Men with New Drug Abuse in Jinan, China.
Arch Sex Behav
January 2025
Department of Public Administration, School of Politics and Public Administration, Guangxi Normal University, Guilin, 541006, Guangxi, China.
Abuse of new drugs, such as Rush poppers, methamphetamine, Magu, Ketamine, and Ecstasy, is common among men who have sex with men (MSM) in China, leading to increased risks of sexually explicit media consumption, sexual violence, and sexual risk behaviors. This study aimed to explore the prevalence and relationships of these behaviors among MSM with new drug abuse. A cross-sectional study was conducted from January to June 2021, involving 453 MSM in Jinan, China.
View Article and Find Full Text PDFDiagnostic accuracy of self-collected tongue swabs for Mycobacterium tuberculosis complex detection in individuals being assessed for TB in South Africa using the Xpert MTB/RIF Ultra assay.
Clin Microbiol Infect
January 2025
Wits Diagnostics Innovation Hub, Health Sciences Research Office, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Objectives: Tongue swabs (TS) have shown potential for detecting Mycobacterium tuberculosis complex (MTBC) through downstream molecular testing. Analytical performance varies, depending on the processing protocol and the molecular test used. This study aimed to first investigate ease-of-use of TS collection in addition to acceptability by individuals being assessed for TB and second to determine the performance of self-collected TS on the Xpert MTB/RIF Ultra (Ultra) assay (Cepheid, Sunnyvale, CA, USA) for MTBC and Rifampicin (RIF) resistance detection.
View Article and Find Full Text PDFNon-tuberculosis mycobacteria identified by line probe assays in respiratory and non-respiratory samples in South Africa between 2015 and 2019.
Tuberculosis (Edinb)
January 2025
Department of Molecular and Cell Biology, University of Cape Town, Cape Town, South Africa. Electronic address:
In recent years, a rise in non-tuberculosis mycobacteria pulmonary disease (NTM-PD) has been reported in several countries. However, data for high-burden tuberculosis settings, including South Africa, is currently limited. In this study, we conducted a retrospective analysis of routine diagnostic data obtained from one diagnostic laboratory in South Africa between 2015 and 2019.
View Article and Find Full Text PDFExperiences of Disclosure, Resilience and Viral Suppression among People Living with HIV in Ghana.
AIDS Behav
January 2025
Department of International Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.
Support for people living with HIV (PLHIV) as they disclose their HIV status can impact continuity of HIV treatment and adherence to antiretrovirals. In the presence of multi-level adversities, resilience among PLHIV can promote health-seeking behaviors and better health outcomes. However, few studies have examined how disclosure experience and resilience work together to impact HIV treatment outcomes among PLHIV.
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