Objectives: To compare mortality among counties (comarques) in Catalonia, Spain for the most frequent malignant tumors.
Methods: Overall mortality data and for five specific tumor sites were analyzed for a five-year period (1983-1989). Crude and site-specific mortality rates were computed. The comparison between counties was adjusted for the 1986 population of Catalonia using the direct method. Comparative mortality ratios (CMR) were obtained for each county with respect to Catalonia.
Results: Overall cancer mortality was higher in the Barcelonès for men and in Osona form women. The CMR for men in the Barcelonès was the highest for cancer of the trachea, bronchi and lungs; the CMR in Solsonès was the highest for stomach cancer, while in Cerdanya it was the highest for colorectal cancer. Among women, the highest CMR for cancer of the trachea, bronchi and lungs was in Montsià, whereas for breast cancer it was Baix Empordà, and Alt Urgell for stomach cancer.
Conclusions: Comparative analyses of cancer mortality by county in Catalonia and sex underscores differences in its distribution, allowing the orientation of cancer control policies and research to be developed in each geographical area.
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http://dx.doi.org/10.1016/s0213-9111(97)71279-2 | DOI Listing |
Lancet Reg Health West Pac
January 2025
National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Beijing, China.
Background: Due to global climate change, high temperature and heatwaves have become critical issues that pose a threat to human health. An effective early warning system is essential to mitigate the health risks associated with high temperature and heatwaves. However, most of the current heatwave early warning systems are not adequately developed based on the heat-health risk model, and the health impact of hot weather has not been well managed in most countries.
View Article and Find Full Text PDFBMC Cancer
January 2025
First Department of Hepatobiliary and Pancreatic Surgery, The Second Affiliated Hospital of Kunming Medical University, Kunming, China.
Pancreatic adenocarcinoma (PAAD) is a highly malignant tumor in the digestive system, with an increasing incidence and mortality rate globally. Recent genetic studies have revealed that the abnormal expression and functional dysregulation of various genes are involved in the occurrence and progression of pancreatic cancer. NIPA-like proteins (NIPAs) are expressed in a variety of cancer types, yet the role of NIPAL1 in cancer remains unclear.
View Article and Find Full Text PDFPublic Health
January 2025
Department of Surgery, Brody School of Medicine at East Carolina University, Greenville, NC, USA.
Objective: To develop and validate a county deprivation index (CDI) that assesses socio-economic disparities and their impact on health outcomes at the county level.
Study Design: A retrospective, cross-sectional study using publicly available county-level data.
Methods: Hierarchical cluster analysis was used to group 18 county-level socio-economic indicators into three clusters: economic well-being and technical connectivity, socio-economic disadvantage and vulnerability, and housing affordability and quality of life.
Cureus
December 2024
Neurosurgery, Federal Fluminense University, Niterói, BRA.
The coexistence of type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD) represents a significant global health challenge, contributing to substantial morbidity, mortality, and economic burden. T2DM is the leading cause of CKD, and CKD exacerbates diabetes-related complications, creating a bidirectional relationship driven by oxidative stress, inflammation, and endothelial dysfunction. Diabetic kidney disease (DKD), affecting some individuals with T2DM, accelerates progression to end-stage renal disease (ESRD) and increases cardiovascular mortality.
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