A uniform study analyzed criteria for evaluation of ecologic jeopardy of some territories. Mortality and disablement appeared to be inadequate for that evaluation. The authors suggest specific parameters for cities neighbouring to major chemical enterprises.
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Nelonemdaz and Patients With Acute Ischemic Stroke and Mechanical Reperfusion: The RODIN Randomized Clinical Trial.
JAMA Netw Open
January 2025
Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Importance: Nelonemdaz selectively antagonizes the 2B subunit of the N-methyl-d-aspartate glutamate receptor and scavenges free radical species.
Objective: To evaluate whether nelonemdaz enhances the clinical outcomes of patients with acute ischemic stroke undergoing emergent reperfusion therapy.
Design, Setting, And Participants: This multicenter double-blind placebo-controlled randomized phase 3 trial (December 25, 2021, to June 30, 2023, in South Korea) recruited patients with acute ischemic stroke who met the following criteria: National Institutes of Health Stroke Scale score greater than or equal to 8, Alberta Stroke Program Early Computed Tomography score greater than or equal to 4, and endovascular thrombectomy within 12 hours after stroke onset.
Effectiveness of a Dentist-based Anti-Smoking Intervention Among Malaysian Adolescents: A Randomized Controlled Field Trial.
Asian Pac J Cancer Prev
January 2025
Department of Community Oral Health and Clinical Prevention, Faculty of Dentistry, Universiti Malaya, Kuala Lumpur, 50603, Malaysia.
Background: The KOTAK program is a national public health initiative in Malaysian primary and secondary schools aimed at reducing youth smoking through school dental services. This study evaluated its effectiveness in Seremban, Negeri Sembilan, Malaysia.
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Systematic review of 99 extremity bone malignancy survival prediction models.
J Orthop Traumatol
January 2025
Department of Medical Imaging, Chi Mei Medical Center, Tainan, Taiwan.
Background: Various prediction models have been developed for extremity metastasis and sarcoma. This systematic review aims to evaluate extremity metastasis and sarcoma models using the utility prediction model (UPM) evaluation framework.
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Brief Scoping Review of Pathways Community Hubs for the Care of Pregnant Mothers and Their Infants.
Matern Child Health J
January 2025
School of Public Health, University of Texas Health Science Center at Houston, 1200 Pressler St, Houston, TX, 77030, USA.
Objectives: Pathways Community Hub (PCH) programs help connect pregnant women to healthcare and social services. A scoping review of peer-reviewed studies on PCHs that reported quantitative outcomes was conducted.
Methods: A search of academic databases from 1901 to 2024 initially yielded a total of 1,312 articles, which was ultimately reduced to 4 articles after duplicates were removed, and two levels of screening were conducted to determine whether studies met the inclusion criteria of evaluating a community hub for pregnant women, was written in English, was peer-reviewed, and reported quantitative outcomes.
Strategies for Fidelity Monitoring a Solution-Focused Brief Intervention in a Randomized Clinical Trial.
J Clin Psychol Med Settings
January 2025
Department of Family and Preventative Medicine, School of Medicine, Emory University, Atlanta, GA, USA.
Integrated Care (IC) models have increased, but the current mechanisms to analyze the efficacy and fidelity of behavioral interventions within IC models are limited. A mixed methods concurrent process evaluation was used within the context of a randomized clinical trial to assess intervention fidelity for a Solution-focused brief therapy (SFBT) intervention implemented within an IC model. A qualitative content analysis was conducted to develop a participant survey and charting template for the SFBT intervention.
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