Severity: Warning
Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 176
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3122
Function: getPubMedXML
File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
Background: The characteristics of shock waves during photoablation were investigated for an IR and a UV laser. These stress waves may be harmful to ocular structures.
Material And Methods: The amplitude of shock waves was measured by a needle-shaped hydrophone in enucleated porcine eyes during excimer laser (193 nm, 23 ns, diameter of ablation 1.5-7.5 mm) and Er:YAG laser photoablation (2.94 microns, 200 microseconds, 1.2 mJ/cm2, diameter of ablation 4 mm).
Results: With the excimer laser at ablation zones larger than 4.5 mm, a pressure focus occurs at a distance of 4-6 mm behind the cornea. The pressure amplitudes are smaller than 80 bar for a fluence of 180 mJ/cm2 and decrease steadily to values below 10 bar towards the retinal level. Higher fluences produce higher pressure values; in the range of 60 to 220 mJ/cm2 the relation is linear. For the Er:YAG laser, pressure amplitudes are smaller than 0.5 bar.
Conclusions: Mechanical damage of the retina is unlikely during excimer-or Er:YAG-laser ablation. The existence of a pressure focus may result in mechanical damages of the posterior lens or anterior vitreous at large ablation diameters. During Er:YAG laser ablation, shock waves could not be detected with our measurements. Theoretical estimations yield values of less than 700 mbar at a fluence of 1.2 J/cm2. The pressure load of the endothelium is independent of diameter but dependent on fluence.
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Source |
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http://dx.doi.org/10.1007/s003470050162 | DOI Listing |
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